Fmoc-Asp-NH2 - CAS 200335-40-6
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Fmoc-Asp-NH2 - CAS 200335-40-6 Catalog number: BADC-01030

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Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
Fmoc-Asp-NH2
CAS
200335-40-6
Catalog Number
BADC-01030
Molecular Formula
C19H18N2O5
Molecular Weight
354.36
Fmoc-Asp-NH2

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BADC-01030 -- $--
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Description
Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
Fmoc-L-Isoasparagine; Fmoc-Isoasn-OH; Butanoic acid, 4-amino-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-oxo-, (3S)-
IUPAC Name
(3S)-4-amino-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxobutanoic acid
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC(=O)O)C(=O)N
InChI
InChI=1S/C19H18N2O5/c20-18(24)16(9-17(22)23)21-19(25)26-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16H,9-10H2,(H2,20,24)(H,21,25)(H,22,23)/t16-/m0/s1
InChIKey
VHRMWRHTRSQVJJ-INIZCTEOSA-N
Density
1.362 g/cm3
Solubility
10 mm in DMSO
Melting Point
185-190 °C
Flash Point
354.2ºC
Index Of Refraction
1.626
LogP
2.94490
PSA
118.72000
Vapor Pressure
1.97E-18mmHg at 25°C
Biological Activity
Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Appearance
White powder
Purity
≥98.0%
Shelf Life
-20℃ 3 years powder; -80℃ 2 years in solvent
Shipping
Room temperature
Storage
-20°C
Boiling Point
662.1 °C at 760 mmHg
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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