2-methyl-2-(pyridin-2-yldisulfanyl)propyl 4-nitrophenyl carbonate incorporates cleavable disulfide linkage and nitrophenyl carbonate for effective payload conjugation and release, enhancing ADC precision and anti-cancer efficacy.
Structure of 1956318-90-3
* For research and manufacturing use only. We do not sell to patients.
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Capabilities & Facilities
2-methyl-2-(pyridin-2-yldisulfanyl)propyl 4-nitrophenyl carbonate, a specialized chemical compound with diverse applications in biosciences and medicinal chemistry. Here are four key applications presented with high perplexity and burstiness:
Protein Modification: This compound enables the selective modification of protein thiols, allowing for in-depth investigations into protein function and structure. By introducing disulfide linkages, researchers can craft stable protein conjugates tailored for a myriad of biochemical assays. Its utility shines in the realm of protein-based therapeutics and diagnostic tools, pushing the boundaries of protein science.
Drug Delivery Systems: At the forefront of pharmaceutical innovation, 2-methyl-2-(pyridin-2-yldisulfanyl)propyl 4-nitrophenyl carbonate plays a pivotal role in designing sophisticated drug delivery systems. Acting as a prodrug linker, it orchestrates the controlled release of active pharmaceutical ingredients under precise conditions. This precision delivery mechanism enables targeted drug administration, minimizing side effects and amplifying therapeutic efficacy, heralding a new era in drug delivery technology.
Chemical Probes: Serving as a versatile chemical probe, this compound stands as a stalwart ally in unraveling intricate biological pathways and deciphering enzyme activities. By engaging with specific amino acid residues, it sheds light on the functions of enzymes and proteins within cellular processes. These probes are indispensable in identifying novel drug targets and advancing the development of therapeutic agents, propelling the field of chemical biology forward.
Bioconjugation: Within the domain of bioconjugation, this compound emerges as a linchpin for securing biomolecules to surfaces or other biomolecules, forming robust conjugates essential for various applications. This process is indispensable in crafting biosensors, immunoassays, and other diagnostic tools. By linking antigens, antibodies, or proteins, it facilitates the sensitive detection of biological markers, empowering diagnostic advancements and bioanalytical research.
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