webinar
Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
Read More

2-methyl-2-(pyridin-2-yldisulfanyl)propyl 4-nitrophenyl carbonate

  CAS No.: 1956318-90-3   Cat No.: BADC-00456   Purity: ≥98% 4.5  

2-methyl-2-(pyridin-2-yldisulfanyl)propyl 4-nitrophenyl carbonate incorporates cleavable disulfide linkage and nitrophenyl carbonate for effective payload conjugation and release, enhancing ADC precision and anti-cancer efficacy.

2-methyl-2-(pyridin-2-yldisulfanyl)propyl 4-nitrophenyl carbonate

Structure of 1956318-90-3

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
ADC Linker
Molecular Formula
C16H16N2O5S2
Molecular Weight
380.44
Shipping
Room temperature

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
-- $-- In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Synonyms
Carbonic acid, 2-​methyl-​2-​(2-​pyridinyldithio)​propyl 4-​nitrophenyl ester ;
IUPAC Name
Canonical SMILES
CC(C)(COC(=O)OC1=CC=C(C=C1)[N+](=O)[O-])SSC2=CC=CC=N2
InChI
InChI=1S/C16H16N2O5S2/c1-16(2,25-24-14-5-3-4-10-17-14)11-22-15(19)23-13-8-6-12(7-9-13)18(20)21/h3-10H,11H2,1-2H3
InChIKey
WQCUUTNIMCNOHP-UHFFFAOYSA-N
Appearance
Soild powder
Shipping
Room temperature

2-methyl-2-(pyridin-2-yldisulfanyl)propyl 4-nitrophenyl carbonate, a specialized chemical compound with diverse applications in biosciences and medicinal chemistry. Here are four key applications presented with high perplexity and burstiness:

Protein Modification: This compound enables the selective modification of protein thiols, allowing for in-depth investigations into protein function and structure. By introducing disulfide linkages, researchers can craft stable protein conjugates tailored for a myriad of biochemical assays. Its utility shines in the realm of protein-based therapeutics and diagnostic tools, pushing the boundaries of protein science.

Drug Delivery Systems: At the forefront of pharmaceutical innovation, 2-methyl-2-(pyridin-2-yldisulfanyl)propyl 4-nitrophenyl carbonate plays a pivotal role in designing sophisticated drug delivery systems. Acting as a prodrug linker, it orchestrates the controlled release of active pharmaceutical ingredients under precise conditions. This precision delivery mechanism enables targeted drug administration, minimizing side effects and amplifying therapeutic efficacy, heralding a new era in drug delivery technology.

Chemical Probes: Serving as a versatile chemical probe, this compound stands as a stalwart ally in unraveling intricate biological pathways and deciphering enzyme activities. By engaging with specific amino acid residues, it sheds light on the functions of enzymes and proteins within cellular processes. These probes are indispensable in identifying novel drug targets and advancing the development of therapeutic agents, propelling the field of chemical biology forward.

Bioconjugation: Within the domain of bioconjugation, this compound emerges as a linchpin for securing biomolecules to surfaces or other biomolecules, forming robust conjugates essential for various applications. This process is indispensable in crafting biosensors, immunoassays, and other diagnostic tools. By linking antigens, antibodies, or proteins, it facilitates the sensitive detection of biological markers, empowering diagnostic advancements and bioanalytical research.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Contact our experts today for pricing and comprehensive details on our ADC offerings.

You May Also Be Interested In

From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.

ADC Linker Development Enzyme Cleavable Linker Cathepsin B Cleavable Linker/Peptide Linker Phosphatase Cleavable Linker β-Glucuronide Linker β-Galactosidase Cleavable Linker Sulfatase Cleavable Linker Chemically Cleavable Linker Non-Cleavable Linker Services Acid Cleavable Linker/Hydrazone Linker

Unlock Deeper ADC Insights

Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.

Linkers - A Crucial Factor in Antibody–Drug Conjugates In-Depth Review of ADC Linkers: Types, Mechanisms, and Research Progress New Structural Insights Solve Instability Issues of Maleimide Linkers in ADCs PEG Linkers in Antibody-Drug Conjugates Peptide Linkers in Antibody-Drug Conjugates Disulfide Linkers in Antibody-Drug Conjugates Biotinylation Reagents in Antibody-Drug Conjugates Maleimide Linkers in Antibody-Drug Conjugates Current ADC Linker Chemistry SPDB Linkers in Antibody-Drug Conjugates

Explore More ADC Products

Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.

ADC Cytotoxin

Powerful Targeted Cancer Solutions

ADC  Cytotoxin with Linker

Enhanced Stability And Efficacy

ADC Linker

Precise Conjugation For Success

Antibody-Drug  Conjugates (ADCs)

Maximized Therapeutic Performance

Auristatins

Next-Level Tubulin Inhibition

Calicheamicins

High-Impact DNA Targeting

Camptothecins

Advanced Topoisomerase Inhibition

Daunorubicins / Doxorubicins

Trusted Anthracycline Payloads

Duocarmycins

Potent DNA Alkylation Agents

Maytansinoids

Superior Microtubule Disruption

Pyrrolobenzodiazepines

Ultra-Potent DNA Crosslinkers

Traditional Cytotoxic Agents

Proven Chemotherapy Solutions

Cleavable Linker

Precise Intracellular Drug Release

Non-Cleavable Linker

Exceptional Long-Term Stability

Historical Records: Me-Tet-PEG4-NHS | DBCO-NH-PEG4-amine | Propargyl-PEG7-acid | 2,5-dioxopyrrolidin-1-yl 4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoate | 3-azidopropanoate-N-hydroxysuccinimide ester | NHPI-PEG3-C2-PFP ester | 4-nitrophenyl 2-(pyridin-2-yldisulfanyl)propyl carbonate | Fmoc-Gly-Gly-Phe-OtBu | NHPI-PEG3-C2-NHS ester | 2,5-dioxopyrrolidin-1-yl 3-Iodo-4-methoxybenzoate | NHPI-PEG2-C2-NHS ester
Send Inquiry
Verification code
Inquiry Basket