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TCO-NHS Ester (axial)

  CAS No.: 1610931-22-0   Cat No.: BADC-01850 4.5  

TCO-NHS Ester (axial) is a trans-cyclooctene functionalized ADC linker designed for fast bioorthogonal conjugation via inverse-electron-demand Diels–Alder reactions, providing site-specific antibody labeling and improved ADC therapeutic performance.

TCO-NHS Ester (axial)

Structure of 1610931-22-0

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Category
ADC Linker
Molecular Formula
C13H17NO5
Molecular Weight
267.28

* For research and manufacturing use only. We do not sell to patients.

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Popular Publications Citing BOC Sciences Products
IUPAC Name
[(2Z)-cyclooct-2-en-1-yl] (2,5-dioxopyrrolidin-1-yl) carbonate
Canonical SMILES
C1CCC=CC(CC1)OC(=O)ON2C(=O)CCC2=O
InChI
InChI=1S/C13H17NO5/c15-11-8-9-12(16)14(11)19-13(17)18-10-6-4-2-1-3-5-7-10/h4,6,10H,1-3,5,7-9H2/b6-4-
InChIKey
IXECMLNTLPRCJD-XQRVVYSFSA-N
Appearance
White to slightly grey crystalline

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Boc-L-Tyr(PEG(3)-N3)-OH | Poc-Cystamine hydrochloride | Fmoc-azetidine-3-carboxylic acid | Boc-L-propraglycine dicyclohexylammonium salt | Azido-PEG(4)-Val-Cit-PAB-PNP | 8-AZido-octanoyl-OSu | Methyl 1-Cbz-azetidine-3-carboxylate | DACN(Tos,Mal) | Aminooxy-PEG2-azide | Nα-Azido-Nε-Boc-L-Lysine | TCO-NHS Ester (axial)
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