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(Me)Tz-butanoic acid

  CAS No.: 1923268-81-8   Cat No.: BADC-01832 4.5  

(Me)Tz-butanoic acid is a methyl-substituted tetrazine ADC linker intermediate, providing fast bioorthogonal inverse-electron-demand Diels–Alder conjugation for site-specific antibody modification and efficient payload delivery in ADCs.

(Me)Tz-butanoic acid

Structure of 1923268-81-8

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ADC Linker
Molecular Formula
C7H10N4O2
Molecular Weight
182.18

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Synonyms
4-Me-tetrazin-butanoic acid
IUPAC Name
4-(6-methyl-1,2,4,5-tetrazin-3-yl)butanoic acid
Canonical SMILES
CC1=NN=C(N=N1)CCCC(=O)O
InChI
InChI=1S/C7H10N4O2/c1-5-8-10-6(11-9-5)3-2-4-7(12)13/h2-4H2,1H3,(H,12,13)
InChIKey
YYIWECNWBYHJIA-UHFFFAOYSA-N

(Me)Tz-butanoic acid, a novel compound with diverse applications in various scientific domains, showcases its versatility across these key areas presented with high perplexity and burstiness.

Pharmaceutical Development: Positioned as a pivotal intermediate in pharmaceutical synthesis, (Me)Tz-butanoic acid offers a promising avenue for crafting novel drug compounds with exceptional therapeutic potential. Researchers are actively exploring its utility in developing cutting-edge antibiotics and anti-inflammatory agents, harnessing its unique structural features to probe its efficacy in combating a range of diseases.

Chemical Synthesis: Embodying a central role in organic chemistry, (Me)Tz-butanoic acid serves as a fundamental building block for synthesizing intricate molecular structures. Chemists leverage its properties to fabricate a diverse array of fine chemicals, agrochemicals, and specialty materials, ushering in novel synthetic pathways that yield compounds of unparalleled purity and specificity.

Biomedical Research: Within the realm of biomedical inquiry, (Me)Tz-butanoic acid emerges as a promising biochemical tool for probing intricate biological processes. By incorporating this compound into assays, scientists delve into enzyme interactions, receptor binding dynamics, and signal transduction pathways, unearthing critical insights into the underlying mechanisms governing human health and disease states.

Polymer Science: Delving into the frontier of polymer science, (Me)Tz-butanoic acid assumes a pivotal role in the design of innovative polymeric materials. Its distinctive properties are poised to shape the development of polymers with bespoke thermal, mechanical, and chemical characteristics, offering potential applications in diverse fields ranging from drug delivery systems to biodegradable plastics and advanced coatings.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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