Inquiry Basket
m-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01150 | -- | $-- | Inquiry |
mPEG7-CH2CH2COONHS ester, a derivative of polyethylene glycol (PEG), plays a crucial role in various bioconjugation processes. Here are four key applications of mPEG7-CH2CH2COONHS ester:
Protein Modification: Widely utilized for pegylating proteins, mPEG7-CH2CH2COONHS ester enhances solubility and stability while mitigating immunogenicity and proteolytic degradation. By appending PEG chains to therapeutic proteins, researchers can prolong their half-life in circulation, resulting in enhanced efficacy and patient adherence. This modification is pivotal in the development of durable biopharmaceuticals that revolutionize the treatment landscape.
Surface Functionalization: Embracing mPEG7-CH2CH2COONHS ester for surface modification of biomaterials and nanoparticles enhances biocompatibility and surface characteristics. PEGylation of surfaces diminishes protein adsorption and cell adhesion, making it suitable for medical devices and drug delivery systems.
Drug Delivery Systems: Integral in formulating drug delivery systems, this ester facilitates the conjugation of drugs to carrier molecules, optimizing pharmacokinetics and biodistribution for superior therapeutic outcomes. By tethering drugs to PEG chains, controlled release and targeted delivery of pharmaceuticals are enhanced, improving treatment precision and efficacy.
Diagnostic Assays: Leveraging mPEG7-CH2CH2COONHS ester to modify biomolecules in diagnostic assays boosts assay sensitivity and stability. By attaching PEG chains to antibodies or antigens, the binding properties and solubility of these biomolecules are fine-tuned, optimizing diagnostic accuracy. This critical step is pivotal in developing robust and sensitive diagnostic tools that drive advancements in medical and research settings.
Customer Support
Providing excellent 24/7 customer service and support
Project Management
Offering 100% high-quality services at all stages
Quality Assurance
Ensuring the quality and reliability of products or services
Global Delivery
Ensuring timely delivery of products worldwide
BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
