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CAS No.: 50586-80-6
Cat No.: BADC-01129
Purity: >98.0%
4.5 
m-PEG2-Tos acts as an intermediate ADC linker with a short PEG2 spacer and tosylate leaving group. It enhances payload solubility and facilitates nucleophilic substitution, supporting reliable conjugation chemistry in antibody-drug conjugate synthesis.
Structure of 50586-80-6
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m-PEG2-Tos, a compound integral to molecular modification, finds diverse applications across scientific and industrial realms. Explore these key applications of m-PEG2-Tos:
Pharmaceutical Development: In the dynamic landscape of pharmaceuticals, m-PEG2-Tos emerges as a pivotal ingredient for enhancing drug solubility and stability. By coupling this compound with therapeutic agents, developers can revolutionize drug delivery mechanisms while mitigating immunogenic responses. This strategic modification holds the promise of elevating treatment efficacy and extending drug circulation within the body.
Protein Modification: Within the intricate realm of protein chemistry, m-PEG2-Tos serves as a catalyst for refining protein characteristics, be it through enhancing solubility or curbing aggregation tendencies. By PEGylating proteins with this compound, scientists unlock avenues for bolstering protein stability and therapeutic efficacy.
Bioconjugation: As a versatile tool in bioconjugation endeavors, m-PEG2-Tos facilitates the grafting of polyethylene glycol (PEG) chains onto diverse molecules like peptides, proteins, or nanoparticles. This process imparts valuable traits such as enhanced solubility and diminished non-specific binding, thus propelling the development of diagnostics and therapeutics with heightened efficiency. The pervasive impact of m-PEG2-Tos in bioconjugation underscores its importance in advancing biomedical technologies.
Biomedical Research: Delving into the intricate nuances of PEGylation, m-PEG2-Tos emerges as a cornerstone in biomedical research, shedding light on the intricate interplay between PEGylation and biological processes. By leveraging this compound, researchers unveil the ripple effects of PEGylation on biomolecular behaviors, ranging from protein-protein interactions to cell membrane permeability. These profound studies elucidate the far-reaching implications of PEGylation in refining drug design paradigms and optimizing delivery systems, charting new horizons in biomedical exploration.
| Catalog | Product Name | CAS | Inquiry |
|---|---|---|---|
| BADC-00875 | m-PEG6-SS-PEG6-methyl | 1007386-15-3 | |
| BADC-00512 | m-PEG1-NHS ester | 1027371-75-0 | |
| BADC-00878 | mPEG6-azide | 1043884-49-6 | |
| BADC-00882 | m-PEG5-succinimidyl carbonate | 1058691-00-1 | |
| BADC-00883 | mPEG7-aldehyde | 1058691-77-2 | |
| BADC-00884 | m-PEG8-Ms | 1059588-19-0 | |
| BADC-00889 | m-PEG8-COOH | 1093647-41-6 | |
| BADC-00890 | mPEG4-bromide | 110429-45-3 | |
| BADC-00519 | m-PEG2-NHS ester | 1127247-34-0 | |
| BADC-00904 | m-PEG7-CH2CH2CHO | 1234369-95-9 |
m-PEG2-Tos
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m-PEG2-Tos
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