Fmoc-NH-PEG3-CH2CH2COOH - CAS 867062-95-1

Fmoc-NH-PEG3-CH2CH2COOH - CAS 867062-95-1 Catalog number: BADC-01171

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Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
Fmoc-NH-PEG3-CH2CH2COOH
CAS
867062-95-1
Catalog Number
BADC-01171
Molecular Formula
C24H29NO7
Molecular Weight
443.49 g/mol
Fmoc-NH-PEG3-CH2CH2COOH
Description
Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid; Fmoc-N-amido-PEG3-acid
IUPAC Name
3-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCC(=O)O
InChI
InChI=1S/C24H29NO7/c26-23(27)9-11-29-13-15-31-16-14-30-12-10-25-24(28)32-17-22-20-7-3-1-5-18(20)19-6-2-4-8-21(19)22/h1-8,22H,9-17H2,(H,25,28)(H,26,27)
InChIKey
CHIDDYZONKDHLG-UHFFFAOYSA-N
Density
1.2±0.1 g/cm3
Solubility
10 mm in DMSO
Flash Point
348.0±31.5 °C
Index Of Refraction
1.562
LogP
2.66
PSA
103.32000
Vapour Pressure
0.0±2.1 mmHg at 25°C
Biological Activity
Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Appearance
Solid
Purity
>98.0%
Shipping
-20°C (International: -20°C)
Storage
Store at -20 ℃, keep in dry and avoid sunlight.
Boiling Point
651.9±55.0 °C at 760 mmHg
Form
Solid

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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