Fmoc-NH-PEG2-CH2CH2COOH - CAS 872679-70-4

Fmoc-NH-PEG2-CH2CH2COOH - CAS 872679-70-4 Catalog number: BADC-01179

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Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

General Information

Category
ADCs Linker
Product Name
Fmoc-NH-PEG2-CH2CH2COOH
CAS
872679-70-4
Catalog Number
BADC-01179
Molecular Formula
C22H25NO6
Molecular Weight
399.44 g/mol

Chemical Structure

  • Fmoc-NH-PEG2-CH2CH2COOH
Purity
>98.0%
Appearance
White to almost white powder to crystal
Synonyms
Fmoc-9-Amino-4,7-Dioxanonanoic acid; Fmoc-N-amido-PEG2-acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oic acid
Solubility
10 mM in DMSO
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Shelf Life
0-4℃ for short term (days to weeks), or -20℃ for long term (months).
Shipping
Room temperature
Melting Point
97 °C
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCC(=O)O
InChI Key
QWHLFJJLRVOHTM-UHFFFAOYSA-N
InChI
InChI=1S/C22H25NO6/c24-21(25)9-11-27-13-14-28-12-10-23-22(26)29-15-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-8,20H,9-15H2,(H,23,26)(H,24,25)
BiologicalActivity
Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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Historical Records: 4-Formyl-N-(2-(o-Tolyloxy)ethyl)benzamide | Fmoc-Gly-Gly-Phe-OH | β-Estradiol-6-CMO-PEG3-biotin | LTx-004 | MC-Val-Cit-PAB-MMAE | Mal-Phe-C4-Val-Cit-PAB | Mc-Val-Cit-PABC-PNP | Amino-PEG9-acid | N-(2-(3,4-dimethylphenoxy)ethyl)-4-formylbenzamide | Mal-PEG4-bis-PEG3-methyltetrazine | Fmoc-NH-PEG2-CH2CH2COOH
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