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DBCO-PEG4-vc-PAB-Duocarmycin TM is a drug-linker conjugate for ADC by using Duocarmycin TM (a potent antitumor antibiotic), linked via DBCO-PEG4-vc-PAB.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-00758 | -- | $-- | Inquiry |
DBCO-PEG4-vc-PAB-Duocarmycin TM, a specialized bioconjugate, finds diverse applications in advanced research and therapy. Explore four key applications:
Targeted Cancer Therapy: Within targeted cancer therapies, DBCO-PEG4-vc-PAB-Duocarmycin TM plays a pivotal role, particularly in the realm of antibody-drug conjugates (ADCs). By coupling this potent drug with cancer-specific antibodies, it enables precise delivery to malignant cells while preserving healthy tissues. This strategic approach enhances treatment efficacy and safety, offering a beacon of hope across various cancer types.
Molecular Probes: As a dynamic tool for probing cellular processes, this bioconjugate stands at the forefront of innovative research. Through conjugation with imaging agents or functional molecules, it empowers researchers to visualize and track specific cellular targets, unraveling the intricacies of cellular dynamics, receptor localization, and drug interactions.
Drug Development: In the realm of drug development, DBCO-PEG4-vc-PAB-Duocarmycin TM assumes a critical role, particularly in optimizing linker chemistry for prodrug design. By delving into release mechanisms and compound stability, scientists can enhance the pharmacokinetics and therapeutic indices of emerging drug candidates, fostering the creation of next-generation therapeutics with superior clinical outcomes.
Biochemical Research: Within biochemical research, this bioconjugate serves as a cornerstone for investigating enzyme-substrate interactions and protein functionality. Through conjugation with specific proteins or peptides, it facilitates targeted delivery of cytotoxic effects, enabling in-depth exploration of cellular pathways and mechanisms. This precise methodology aids in dissecting complex biological processes, offering potential insights into novel therapeutic targets.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
