DBCO-PEG4-GGFG-DMEA-PNU159682 Catalog number: BADC-01421

Description

DBCO-PEG4-GGFG-DMEA-PNU159682 is a click-reactive drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs).

Synonyms

N-[20-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-17,20-dioxo-4,7,10,13-tetraoxa-16-azaicosan-1-oyl]glycylglycyl-L-phenylalanyl-N-methyl-N-{2-[methyl({2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-4-{[(1S,3R,4aS,9S,9aR,10aS)-9-methoxy-1-methyloctahydro-1H-pyrano[4',3':4,5][1,3]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy}-6,11-dioxo-1,2,3,4,6,11-hexahydro-2-tetracenyl]ethoxy}carbonyl)amino]ethyl}glycinamide; Glycinamide, N-[20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1,17,20-trioxo-4,7,10,13-tetraoxa-16-azaeicos-1-yl]glycylglycyl-L-phenylalanyl-N-[2-[[[2-[(2S,4S)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-4-[[(1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy]-6,11-dioxo-2-naphthacenyl]-2-oxoethoxy]carbonyl]methylamino]ethyl]-N-methyl-

InChI

InChI=1S/C82H97N9O25/c1-49-77-58(90-30-33-112-80(107-5)79(90)116-77)41-68(114-49)115-60-43-82(105,42-55-70(60)76(102)72-71(74(55)100)73(99)54-19-13-21-59(106-4)69(54)75(72)101)61(92)48-113-81(104)89(3)29-28-88(2)67(98)46-86-78(103)56(40-50-14-7-6-8-15-50)87-65(96)45-85-64(95)44-84-63(94)26-31-108-34-36-110-38-39-111-37-35-109-32-27-83-62(93)24-25-66(97)91-47-53-18-10-9-16-51(53)22-23-52-17-11-12-20-57(52)91/h6-21,49,56,58,60,68,77,79-80,100,102,105H,24-48H2,1-5H3,(H,83,93)(H,84,94)(H,85,95)(H,86,103)(H,87,96)/t49-,56-,58-,60-,68-,77+,79+,80-,82-/m0/s1

InChIKey

VTRDFAIGBFUTST-LNNNDNRNSA-N

Density

1.5±0.1 g/cm3