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DBCO-NHCO-PEG4-NHS ester

  CAS No.: 2100306-58-7   Cat No.: BADC-01059   Purity: ≥95% 4.5  

DBCO-NHCO-PEG4-NHS ester is a click-ready ADC linker for copper-free strain-promoted azide-alkyne cycloaddition (SPAAC). Featuring NHS ester reactivity and a hydrophilic PEG spacer, it's ideal for site-specific, bioorthogonal conjugation in antibody-drug conjugate construction.

DBCO-NHCO-PEG4-NHS ester

Structure of 2100306-58-7

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Category
ADC Linker
Molecular Formula
C34H39N3O10
Molecular Weight
649.69
Shipping
Room temperature
Storage
Store at -20 °C, keep in dry and avoid sunlight.

* For research and manufacturing use only. We do not sell to patients.

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Popular Publications Citing BOC Sciences Products
Synonyms
DBCO-NHCO-PEG4-NHS; (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]propanoate; 2,5-dioxopyrrolidin-1-yl 1-[(3-{2-azatricyclo[10.4.0.0,hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-3-oxopropyl)carbamoyl]-3,6,9,12-tetraoxapentadecan-15-oate; 4,7,10,13-Tetraoxa-17-azaeicosanoic acid, 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-16,20-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
IUPAC Name
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCC(=O)NCCC(=O)N2CC3=CC=CC=C3C#CC4=CC=CC=C42
InChI
InChI=1S/C34H39N3O10/c38-30(35-16-13-31(39)36-25-28-7-2-1-5-26(28)9-10-27-6-3-4-8-29(27)36)14-17-43-19-21-45-23-24-46-22-20-44-18-15-34(42)47-37-32(40)11-12-33(37)41/h1-8H,11-25H2,(H,35,38)
InChIKey
ZVWIDTHUTOSOEZ-UHFFFAOYSA-N
Solubility
10 mm in DMSO
Appearance
Solid
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
Room temperature
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Form
Solid

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Boc-Aminooxy-PEG2-bromide | Azido-PEG4-t-butyl acetate | TCO-PEG12-NHS ester | Amino-PEG8-t-butyl ester | DBCO-Peg4-VC-PAB-MMAE | DBCO-PEG5-NHS ester | mPEG11-amine | Fmoc-Gly-Gly-OH | Tetraethylene glycol monotosylate | Amino-ethyl-SS-PEG3-NHBoc | DBCO-NHCO-PEG4-NHS ester
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