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6-Maleimidocaproic acid sulfo-NHS is a small molecule reagent used in the biomedical industry. It is commonly used to modify biomolecules, such as proteins and antibodies, for site-specific conjugation. This compound enables the efficient and stable attachment of drugs, tags, or targeting moieties to these biomolecules, thereby facilitating the development of innovative treatments for a variety of diseases, including cancer and autoimmune diseases.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-00505 | -- | $-- | Inquiry |
6-Maleimidocaproic acid sulfo-NHS, a highly reactive crosslinking reagent, is extensively utilized in biochemical and biotechnological applications. Here are four key applications of this compound, presented with a high degree of perplexity and burstiness:
Protein Labeling: Serving as a fundamental tool in protein research, 6-Maleimidocaproic acid sulfo-NHS plays a crucial role in covalently attaching fluorescent dyes or other labels to proteins. By interacting with free amine groups on proteins, it facilitates precise and durable labeling essential for various analytical techniques like fluorescence microscopy and flow cytometry. This capability enhances the ability to monitor and analyze protein dynamics within diverse cellular environments, unveiling new dimensions in the exploration of protein function.
Antibody Conjugation: At the heart of therapeutic and diagnostic pursuits, this reagent is pivotal in skillfully conjugating antibodies with drugs, toxins, or enzymes. Through the formation of steadfast thioether bonds with sulfhydryl groups, it ensures targeted and effective delivery of the conjugated molecules. This application stands as a cornerstone in advancing targeted cancer therapies and developing diagnostic assays, ushering in new possibilities for precision medicine and disease detection.
Surface Immobilization: In the realms of biosensing and biochip technologies, 6-Maleimidocaproic acid sulfo-NHS emerges as a critical agent for immobilizing biomolecules onto various surfaces. By establishing a durable linkage between the biomolecule and the sensor surface, it enhances the sensitivity and specificity of biosensing devices. This functionality proves particularly crucial in creating diagnostic tools capable of detecting biomarkers and pathogens, heralding a new era in rapid and accurate disease diagnosis.
Protein-Protein Interaction Studies: Unveiling the intricacies of cellular signaling and molecular dynamics, this crosslinking reagent is invaluable for probing protein-protein interactions. By bridging proteins in close proximity, it empowers researchers to unravel and delineate intricate interaction networks crucial for understanding complex biological processes.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
