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1-Iodo-2-(2-(2-methoxyethoxy)ethoxy)ethane

  CAS No.: 62999-96-6   Cat No.: BADC-01550   Purity: 98% +(stabilized with Copper chip) 4.5  

1-Iodo-2-(2-(2-methoxyethoxy)ethoxy)ethane is a PEGylated halide ADC linker intermediate that supports nucleophilic substitution reactions for effective payload conjugation and improved solubility in antibody-drug conjugates.

1-Iodo-2-(2-(2-methoxyethoxy)ethoxy)ethane

Structure of 62999-96-6

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ADC Linker
Molecular Formula
C7H15IO3
Molecular Weight
274.1

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Synonyms
Ethane, 1-(2-iodoethoxy)-2-(2-methoxyethoxy)-; 1-[2-(2-iodoethoxy)ethoxy]-2-methoxyethane; 1-Iodo-3,6,9-trioxadecane; 1-iodo-2-(2-(2-methoxyethoxy)ethoxy)ethane
IUPAC Name
1-[2-(2-iodoethoxy)ethoxy]-2-methoxyethane
Canonical SMILES
COCCOCCOCCI
InChI
InChI=1S/C7H15IO3/c1-9-4-5-11-7-6-10-3-2-8/h2-7H2,1H3
InChIKey
DLGFZOSPWIUMKY-UHFFFAOYSA-N
Solubility
Soluble
Pictograms
Toxic; Health hazard
Signal Word
Danger

1-Iodo-2-(2-(2-methoxyethoxy)ethoxy)ethane is a remarkably versatile chemical compound with a wide array of applications in synthetic and materials chemistry. Here are four key applications presented with high perplexity and burstiness:

Organic Synthesis: 1-Iodo-2-(2-(2-methoxyethoxy)ethoxy)ethane serves as a pivotal reagent in organic synthesis, facilitating the incorporation of iodine functionalities into molecules. This compound actively engages in substitution reactions, leading to the formation of crucial carbon-iodine bonds that serve as pivotal intermediates in the synthesis of intricate organic molecules. Its versatility in modifying polyethers and other polymer backbones makes it an indispensable tool in the realm of materials science explorations.

Pharmaceutical Development: In the innovative realm of pharmaceutical development, 1-Iodo-2-(2-(2-methoxyethoxy)ethoxy)ethane emerges as a key player, serving as a precursor in the synthesis of biologically active molecules. Its unique structural configuration enables the introduction of iodine atoms into drug candidates, thereby augmenting properties like metabolic stability and bioavailability. This compound plays a vital role in fostering the creation of novel therapeutics endowed with enhanced pharmacokinetic profiles, ushering in a new era of pharmaceutical advancements.

Polymer Chemistry: Dive into the intricate world of polymer chemistry with 1-Iodo-2-(2-(2-methoxyethoxy)ethoxy)ethane as your guide. This compound finds its niche in the realm of modifying polymers and enhancing their properties. By grafting iodine functionalities onto polymer chains, it opens up avenues for further chemical modifications, paving the way for the development of advanced materials boasting specific mechanical, thermal, and chemical characteristics. Witness the transformative power of this compound in shaping the landscape of polymer science.

Radiolabeling in Medical Imaging: Step into the realm of medical imaging and radiochemistry with 1-Iodo-2-(2-(2-methoxyethoxy)ethoxy)ethane at the forefront. This compound finds its footing in the synthesis of radiolabeled molecules, offering a gateway to the world of radioisotopes. By replacing iodine with isotopes such as I-123 or I-131, this compound fuels the advancement of nuclear medicine, enabling the development of radiopharmaceuticals tailored for targeted imaging and therapeutic interventions in various disease states. Experience the convergence of chemistry and medicine in the realm of radiolabeling, driven by the remarkable capabilities of this compound.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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