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Vascular Nano-Delivery Using Tropism and Targeting
Vladimir R. Muzykantov, MD, PhD | Founding Co-Director, CT3N at UPenn
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Cleavable Linker

Cleavable linkers are a core component of antibody-drug conjugates (ADCs) and various bioconjugation systems, responsible for stably connecting antibodies, proteins, peptides, or small-molecule drugs to active payloads while enabling precise release in specific biological environments. With the advancement of precision medicine and targeted drug development, the design, chemical properties, and triggering mechanisms of cleavable linkers play a decisive role in the efficacy, safety, and therapeutic index of ADCs. BOC Sciences is dedicated to providing high-quality cleavable linker products and customized services to clients worldwide. We offer over 1,000 different types of linkers, including acid-sensitive, enzymatically cleavable, disulfide-based, and pH-sensitive linkers, catering to diverse research and development needs. All products comply with GMP standards, ensuring stability in circulation and precise release within the tumor microenvironment.

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