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N-(2-(4-Ethoxyphenoxy)ethyl)-4-Formylbenzamide

  CAS No.: 1226072-27-0   Cat No.: BADC-00548 4.5  

N-(2-(4-Ethoxyphenoxy)ethyl)-4-Formylbenzamide serves as an aldehyde-functionalized ADC linker, supporting rapid and selective antibody conjugation to optimize drug delivery efficiency in ADCs.

N-(2-(4-Ethoxyphenoxy)ethyl)-4-Formylbenzamide

Structure of 1226072-27-0

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ADC Linker
Molecular Formula
C18H19NO4
Molecular Weight
313.35
Shipping
Room temperature

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IUPAC Name
N-[2-(4-ethoxyphenoxy)ethyl]-4-formylbenzamide
Canonical SMILES
CCOC1=CC=C(C=C1)OCCNC(=O)C2=CC=C(C=C2)C=O
InChI
InChI=1S/C18H19NO4/c1-2-22-16-7-9-17(10-8-16)23-12-11-19-18(21)15-5-3-14(13-20)4-6-15/h3-10,13H,2,11-12H2,1H3,(H,19,21)
InChIKey
GPJZOBBCQSQCRM-UHFFFAOYSA-N
Shipping
Room temperature

N-(2-(4-Ethoxyphenoxy)ethyl)-4-Formylbenzamide is an organic compound garnering attention within the pharmaceutical and chemical industries due to its versatile applications. The inclusion of an ethoxyphenoxy group in its structure suggests potential use in the development of novel therapeutic agents. This particular arrangement facilitates notable interactions with biological systems, typically offering improved solubility and bioavailability over similar compounds lacking the ethoxy group. It primarily stands out in anti-inflammatory therapy research, where its efficacy in modulating cytokine and chemokine pathways could lead to breakthroughs in the treatment of chronic inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.

In medicinal chemistry, N-(2-(4-Ethoxyphenoxy)ethyl)-4-Formylbenzamide is of interest as a scaffold for designing multi-target drugs. The compound's backbone allows for the addition of various substituents, making it a versatile starting point for creating multifunctional molecules aimed at complex disorders, including neurodegenerative diseases like Alzheimer's. By altering the formyl functional group or the ethoxy segment, researchers can fine-tune the molecule's affinity and selectivity for different biological targets. This adaptability not only streamlines the drug discovery process but also aids in producing compounds with the potential to engage multiple pathological pathways simultaneously, an approach increasingly valuable for treating multifaceted diseases.

Beyond the biomedical sphere, N-(2-(4-Ethoxyphenoxy)ethyl)-4-Formylbenzamide holds promise in materials science, particularly in the synthesis of functional polymers and advanced materials. The unique physicochemical properties imparted by the ethoxyphenoxy moiety allow this compound to be integrated into complex polymer matrices, potentially leading to advancements in creating sustainable materials with specific mechanical and chemical properties. Its reactivity can be leveraged in forming cross-linked polymer networks that enhance durability and performance, especially useful in high-stress environments or as coatings that demand specific resistance features.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: N-(2-(2,4-Dimethylphenoxy)ethyl)-4-Formylbenzamide | Daun02 | 4-Formyl-N-(2-Methoxyethyl)benzamide | MC-Sq-Cit-PAB-Gefitinib | NHPI-PEG4-C2-PFP ester | N-(2-(4-Ethoxyphenoxy)ethyl)-4-Formylbenzamide
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