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N-(2-(2, 5-Dimethylphenoxy)ethyl)-4-formylbenzamide is a linker for antibody-drug-conjugation (ADC).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-00561 | -- | $-- | Inquiry |
N-(2-(2,5-Dimethylphenoxy)ethyl)-4-Formylbenzamide is a promising compound with a range of applications in drug development, particularly in the field of cancer therapy. The structure of this molecule, featuring a formylbenzamide group, allows it to interact selectively with key biological targets involved in tumor growth and metastasis. By incorporating this compound into targeted drug delivery systems, it enables the precise delivery of therapeutic agents to cancer cells, enhancing the therapeutic efficacy while minimizing side effects. This selectivity is essential for the development of more effective and less toxic treatments for cancer.
A significant application of N-(2-(2,5-Dimethylphenoxy)ethyl)-4-Formylbenzamide lies in the design of small-molecule inhibitors targeting critical enzymes involved in cancer progression. The dimethylphenoxyethyl group enhances the compound’s hydrophobic interactions, which improves its bioavailability and cellular uptake. Once inside the cells, it can inhibit specific enzymes or signaling pathways that promote cancer cell survival and proliferation, such as those driven by protein kinases or proteases. This inhibition can result in slowed tumor growth and increased sensitivity to chemotherapy, contributing to improved treatment outcomes.
In addition to its therapeutic applications, N-(2-(2,5-Dimethylphenoxy)ethyl)-4-Formylbenzamide is being explored for use in diagnostic imaging, particularly in cancer detection. When conjugated with imaging agents like fluorescent dyes or radionuclides, it can be used to specifically target and visualize cancerous tissues. This capability allows for non-invasive imaging of tumors, which aids in monitoring disease progression, evaluating the response to therapies, and assisting in surgical planning. Such precise imaging techniques are crucial for advancing personalized medicine in oncology, where treatment can be tailored to the specific characteristics of an individual’s tumor.
The compound is also of interest for its potential role in the development of anti-inflammatory agents. The formylbenzamide group has the potential to modulate various inflammatory pathways, such as those mediated by cyclooxygenases or pro-inflammatory cytokines. By targeting these pathways, N-(2-(2,5-Dimethylphenoxy)ethyl)-4-Formylbenzamide could be developed into a therapeutic agent for chronic inflammatory diseases, such as rheumatoid arthritis or inflammatory bowel disease. Its targeted approach would provide a more precise modulation of the immune response, potentially leading to more effective treatments with fewer side effects than traditional anti-inflammatory drugs.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
