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Azido-PEG3-PFP ester is a key tool for biomolecule modification. By facilitating azide group conjugation with target molecules, it imparts a platform for seamless bioorthogonal labeling and imaging throughout diverse biological frameworks. Its versatile employment encompasses drug delivery, proteomics, and bioconjugation strategies, unveiling a profound comprehension of cellular pathways and disease mechanisms.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-00406 | -- | $-- | Inquiry |
Azido-PEG3-PFP ester is a versatile reagent commonly used in bioconjugation and chemical biology. Here are some key applications of Azido-PEG3-PFP ester:
Click Chemistry: Azido-PEG3-PFP ester is a pivotal compound in click chemistry, enabling the formation of stable covalent bonds between biomolecules. It reacts with alkynes in the presence of a copper catalyst, facilitating the attachment of various functional groups to proteins, nucleic acids, or other molecules. This application is central to creating bioconjugates for imaging, diagnostics, and therapeutic purposes.
Protein Labeling: This reagent is used for site-specific labeling of proteins, allowing the introduction of azide groups into protein structures. The azide-functional group can later react with alkyne- or cyclooctyne-modified probes for detection or immobilization. This precise labeling technique is crucial for studying protein interactions, tracking protein dynamics, and developing biosensors.
Drug Delivery Systems: Azido-PEG3-PFP ester is instrumental in developing advanced drug delivery systems. It facilitates the attachment of therapeutic agents to PEGylated carriers, enhancing drug solubility, stability, and bioavailability. This strategy is employed to improve the pharmacokinetic profiles of drugs, targeting them more effectively to disease sites while reducing side effects.
Surface Modification: This ester can be used to modify the surface properties of various materials, including nanoparticles, hydrogels, and medical devices. By introducing azido groups onto surfaces, it provides reactive sites for further functionalization through click reactions. This capability is crucial for applications in tissue engineering, biosensing, and the development of biocompatible materials.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
