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4-Maleimidobutyric Acid is a short crosslinking reagent.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01625 | -- | $-- |
4-Maleimidobutyric acid, a versatile chemical compound used in diverse research and industrial settings, finds applications across various domains. Here are four key applications highlighted with elevated perplexity and burstiness:
Bioconjugation: A cornerstone of modern biochemistry, 4-Maleimidobutyric acid plays a vital role in conjugating proteins, peptides, and antibodies with other molecules like drugs or fluorescent labels. Its maleimide group exhibits selective reactivity with thiol groups, enabling precise coupling under gentle conditions. This method is crucial for crafting targeted therapeutics and diagnostic tools tailored to specific molecular interactions.
Drug Delivery: Positioned at the forefront of pharmaceutical innovation, 4-Maleimidobutyric acid contributes to the design of advanced drug delivery systems that ensure the controlled and targeted release of therapeutic agents. By linking drugs to polymeric carriers or nanoparticles, it enhances drug stability and specificity, ultimately improving treatment efficacy while minimizing undesirable side effects. This approach represents a paradigm shift in drug delivery strategies.
Surface Modifications: Delving into the realm of biomaterials, 4-Maleimidobutyric acid is instrumental in enhancing the biocompatibility and functionality of material surfaces. By grafting bioactive molecules, such as adhesion-promoting peptides or antifouling agents, it enhances material-biological interactions crucial for developing cutting-edge medical implants and biosensors. This application showcases the synergy between chemistry and biomedicine in creating advanced biofunctional materials.
Enzyme Immobilization: At the intersection of biocatalysis and industrial applications, 4-Maleimidobutyric acid facilitates the immobilization of enzymes on diverse supports, elevating their stability and reusability in enzymatic reactions. Through covalent bonding between the maleimide group and enzyme thiol groups, enzymes are firmly anchored onto carrier materials, ensuring consistent performance over multiple cycles. This technique is pivotal for industries reliant on enzymatic processes, underscoring the importance of enzyme stability in enhancing productivity and efficiency.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
