11-Azidoundecanoic acid acts as a hydrophobic bioconjugation linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry.
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BADC-01644 | -- | $-- | Inquiry |
11-Azidoundecanoic acid, a versatile compound with unique chemical properties, finds applications across bioscience and materials science. Here are four key applications presented with high perplexity and burstiness:
Bioconjugation: Serving as a cornerstone in bioconjugation techniques, 11-Azidoundecanoic acid facilitates the attachment of biomolecules to surfaces or other biomolecules. Its azide group enables precise and efficient conjugation via click chemistry, unlocking avenues for studying protein interactions, enzyme activities, and cell surface modifications. This indispensable application plays a pivotal role in the development of diagnostic tools and therapeutic delivery systems, driving innovation in biomedicine.
Material Science: In the realm of material science, 11-Azidoundecanoic acid plays a vital role in surface modification, enhancing material properties such as hydrophobicity, conductivity, and bioactivity by introducing functional groups. Through click chemistry with alkyne-modified surfaces, customized nanomaterials and coatings can be crafted, elevating material performance in biomedical devices, sensors, and other cutting-edge applications. This innovation reshapes the landscape of material engineering, ushering in new possibilities for advanced technologies.
Polymer Chemistry: Embracing controlled radical polymerization techniques, 11-Azidoundecanoic acid is a key player in the synthesis of functional polymers. Its azide functionality allows for post-polymerization modifications, facilitating the incorporation of diverse functional groups. This capability is instrumental in designing intelligent polymers with tailored properties for applications in drug delivery, tissue engineering, and responsive materials, revolutionizing the field of polymer chemistry with its versatility and precision.
Chemical Biology: In the realm of chemical biology, 11-Azidoundecanoic acid serves as a vital chemical reporter for investigating biological processes. Through its integration into biomolecules, it serves as a tracer for molecular interactions and dynamics within cells, offering invaluable insights into cellular mechanisms, protein functions, and metabolic pathways. This technique deepens our comprehension of complex biological systems, pushing the boundaries of knowledge in chemical biology and paving the way for groundbreaking discoveries.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.