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| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-00978 | -- | $-- | Inquiry |
MC-Val-Ala-PAB-PNP, a chemical compound utilized in bioconjugation and prodrug design, plays a pivotal role in various applications.
Prodrug Development: In the realm of prodrug development, MC-Val-Ala-PAB-PNP shines as a crucial linker that triggers the release of active drugs in response to specific enzymatic signals. This functionality allows for the creation of targeted therapies that activate precisely at the intended site, mitigating off-target effects and elevating therapeutic effectiveness. Notably, its utility in cancer treatment underscores the importance of accurate drug delivery for optimal outcomes.
Peptide Drug Conjugation: Within the domain of peptide drug conjugation, MC-Val-Ala-PAB-PNP assumes the role of a cleavable linker, facilitating the connection between therapeutic peptides and carrier molecules or medications. This connection bolsters the stability and half-life of peptide drugs, enhancing their pharmacokinetic properties. The controlled release mechanism of MC-Val-Ala-PAB-PNP ensures that peptides are liberated at the designated site, amplifying the efficacy of treatments.
Targeted Drug Delivery: MC-Val-Ala-PAB-PNP's involvement in targeted drug delivery systems is noteworthy, as it binds drugs to antibodies or other targeting agents. While remaining stable in circulation, this compound releases the drug upon binding to the designated target, such as tumor cells or specific tissue types. This targeted strategy minimizes systemic exposure and diminishes potential side effects, exemplifying precision in drug delivery.
Biochemical Research: Within biochemical research settings, MC-Val-Ala-PAB-PNP serves as a valuable tool for investigating enzyme activity and substrate specificity. Its cleavable nature provides researchers with insights into enzyme kinetics and biochemical pathways, fostering effective exploration in the field. Unveiling the interactions between MC-Val-Ala-PAB-PNP and enzymes holds the promise of identifying novel therapeutic targets and enhancing strategies for drug design.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, non-natural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
