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Mc-O-Si(di-iso)-Cl is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) ).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01282 | -- | $-- | Inquiry |
Mc-O-Si(di-iso)-Cl is a versatile chemical reagent commonly used in organic synthesis, particularly in the modification of molecular structures for various applications. Its unique silicon-containing group makes it an effective tool for introducing reactive functional groups into organic compounds. This reagent is widely utilized in the creation of intermediates for pharmaceutical development, material science, and chemical research, allowing for precise modifications of chemical properties and enhancing the performance of final products.
One of the key applications of Mc-O-Si(di-iso)-Cl is in the synthesis of silicon-based materials. The presence of a silicon atom in its structure enables Mc-O-Si(di-iso)-Cl to act as a linking agent or crosslinker in the development of advanced materials, such as polysiloxanes, siloxane-based polymers, and hybrid organic-inorganic materials. These materials are used in a wide range of industries, including electronics, coatings, and sealants, due to their unique properties such as heat resistance, electrical insulation, and enhanced mechanical strength.
Mc-O-Si(di-iso)-Cl is also applied in the synthesis of complex molecules and drug candidates. The silicon group can be selectively functionalized or incorporated into bioactive molecules, improving their solubility, stability, and bioavailability. In pharmaceutical chemistry, Mc-O-Si(di-iso)-Cl is particularly useful in modifying compounds to optimize their pharmacokinetic properties. This makes it an important tool for designing more effective and targeted drug delivery systems. It can also be used in the synthesis of prodrugs, which are converted into active drugs within the body.
In addition, Mc-O-Si(di-iso)-Cl is utilized in surface modification processes, particularly in the creation of functionalized surfaces for various applications in materials science. It can be used to attach functional groups to surfaces, improving adhesion, wettability, and chemical reactivity. This property is essential in the production of advanced coatings, sensors, and catalysts, where specific surface properties are crucial for performance. Its ability to modify surfaces at the molecular level allows for the creation of highly specialized materials with tailored properties.
Finally, Mc-O-Si(di-iso)-Cl has applications in the field of nanotechnology. The versatility of its silicon-based structure allows it to be used as a precursor for the development of nanomaterials, such as silica nanoparticles and nanocomposites. These materials are employed in a variety of applications, including drug delivery, imaging, and diagnostics. The ability to functionalize these nanoparticles with specific chemical groups using Mc-O-Si(di-iso)-Cl provides a powerful tool for creating customizable nanomaterials with enhanced properties for diverse technological and medical applications.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
