Name: Mal-EGGGG-PEG8-amide-bis(deoxyglucitol)
Brand: BOC Sciences
Rating: 5 (1 reviews)

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IUPAC Name

(4S)-5-[[2-[[2-[[2-[[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-[[(2S)-1,5-dioxo-1,5-bis[[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]amino]pentan-2-yl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-4-[[2-(2,5-dioxopyrrol-1-yl)acetyl]amino]-5-oxopentanoic acid

Canonical SMILES

C1=CC(=O)N(C1=O)CC(=O)NC(CCC(=O)O)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NC(CCC(=O)NCC(C(C(C(CO)O)O)O)O)C(=O)NCC(C(C(C(CO)O)O)O)O

InChI

InChI=1S/C55H94N10O31/c66-32-38(70)52(85)50(83)36(68)25-57-40(72)3-1-34(54(87)61-26-37(69)51(84)53(86)39(71)33-67)63-41(73)7-9-89-11-13-91-15-17-93-19-21-95-23-24-96-22-20-94-18-16-92-14-12-90-10-8-56-42(74)27-58-43(75)28-59-44(76)29-60-45(77)30-62-55(88)35(2-6-49(81)82)64-46(78)31-65-47(79)4-5-48(65)80/h4-5,34-39,50-53,66-71,83-86H,1-3,6-33H2,(H,56,74)(H,57,72)(H,58,75)(H,59,76)(H,60,77)(H,61,87)(H,62,88)(H,63,73)(H,64,78)(H,81,82)/t34-,35-,36-,37-,38+,39+,50+,51+,52+,53+/m0/s1

InChIKey

VSCPNQGDWPYXJQ-QPEMRJNGSA-N

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Mal-EGGGG-PEG8-amide-bis(deoxyglucitol), a custom-designed compound with diverse applications in bioscience and biotechnology, offers numerous possibilities.

Drug Delivery Systems: A versatile compound, Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) serves as a critical linker in prodrug systems, enhancing the solubility and stability of pharmaceutical molecules. When tethered to therapeutic agents, it enables precise control over drug release, targeting specific tissues or cells with enhanced efficiency. Such tailored systems not only optimize drug pharmacokinetics and biodistribution but also minimize undesirable side effects.

Bioconjugation: Embracing its role as a spacer molecule, Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) engages in bioconjugation endeavors, bridging biomolecules like proteins or peptides with synthetic complexes. Through offering robust and flexible connections, it upholds the biological activity and integrity of the attached biomolecules.

Nanoparticle Functionalization: Unleashing its potential in nanoparticle functionalization, this compound elevates the stability and bioavailability of nanoparticles in biomedical settings. By anchoring onto nanoparticle surfaces, it enhances their targeting prowess and mitigates nonspecific interactions within the body.

Hydrogel Formation: Fostering the creation of hydrogels with tailored properties, Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) integrates seamlessly into polymer matrices. These specialized hydrogels find diverse applications in tissue engineering, wound healing, and drug delivery systems, offering a conducive milieu for cell proliferation and controlled release of bioactive compounds.