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Mal(Br2)-Aca-OSu - CAS 2389064-41-7

Mal(Br2)-Aca-OSu - CAS 2389064-41-7 Catalog number: BADC-02026

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Mal(Br2)-Aca-OSu is a bioconjugation reagent used in antibody-drug conjugate (ADC) synthesis. It features a dibromo maleimide group and an aminocaproic acid (Aca) linker, terminated with an N-hydroxysuccinimide (OSu) ester. This compound is designed for conjugating antibodies to cytotoxic drugs, with the dibromo maleimide group facilitating selective attachment to thiol groups in the antibody.

Category
ADC Linker
Product Name
Mal(Br2)-Aca-OSu
CAS
2389064-41-7
Catalog Number
BADC-02026
Molecular Formula
C14H14Br2N2O6
Molecular Weight
466.08
Purity
>96%
Mal(Br2)-Aca-OSu

Ordering Information

Catalog Number Size Price Quantity
BADC-02026 -- $-- Inquiry
Synonyms
3,4-Dibrommaleimido-aminohexanoic acid NHS ester; Dibrommaleimido aminocaproic acid NHS ester; DB-Aca-OSu; DBM-Aca-OSu; DB-Aca-NHS; DBM-Aca-NHS; 2,5-Dioxopyrrolidin-1-yl 6-(3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate; 1H-Pyrrole-1-hexanoic acid, 3,4-dibromo-2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester; DBM-Hexanonate NHS
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 6-(3,4-dibromo-2,5-dioxopyrrol-1-yl)hexanoate
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCCCCN2C(=O)C(=C(C2=O)Br)Br
InChI
InChI=1S/C14H14Br2N2O6/c15-11-12(16)14(23)17(13(11)22)7-3-1-2-4-10(21)24-18-8(19)5-6-9(18)20/h1-7H2
InChIKey
XQPDBTBEBDUMLN-UHFFFAOYSA-N
Density
1.89±0.1 g/cm3
Storage
Store at 2-8 °C
Boiling Point
511.6±60.0 °C at 760 mmHg
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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