Hynic-PEG3-N3 is an azido-functionalized PEG linker with HYNIC group, used in ADCs for radiolabeling and click chemistry bioconjugation, enhancing targeted drug delivery and diagnostic applications.
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Capabilities & Facilities
Hynic-PEG3-N3, a versatile chemical compound utilized in various bioconjugation and biomedical applications, offers a wide array of functionalities. Here are four key applications of Hynic-PEG3-N3:
Radiopharmaceutical Development: In radiopharmaceutical synthesis for diagnostic imaging, Hynic-PEG3-N3 merges seamlessly with peptides or antibodies, allowing for the introduction of radioisotopes tailored for PET or SPECT imaging. This integration unveils a realm where biological processes can be visualized and monitored in vivo, enhancing disease diagnosis and progression tracking.
Drug Delivery Systems: In the realm of targeted drug delivery, Hynic-PEG3-N3 acts as a pivotal link between therapeutic agents and targeting molecules like antibodies or peptides. Through the use of the PEG3 spacer, the solubility and stability of the drug conjugate are bolstered, amplifying bioavailability. This precise delivery strategy ushers in a new era where drugs reach specific tissues or cells with utmost accuracy, potentially mitigating side effects and elevating therapeutic efficacy.
Bioconjugation: Hynic-PEG3-N3 facilitates the attachment of biomolecules to diverse substrates or other biomolecules. The azide functional group (-N3) unlocks the realm of Click Chemistry reactions, enabling the seamless and selective coupling of proteins, nucleic acids, and other biomolecules. This technique lies at the heart of biosensor, diagnostic, and therapeutic agent development, offering a platform for innovative advancements.
Molecular Imaging: Hynic-PEG3-N3 shines as a beacon in imaging probe preparation. Through the conjugation of Hynic-PEG3-N3 with targeted ligands, researchers craft imaging agents that hone in on specific biomarkers or cellular receptors. These probes serve as vital tools in non-invasive imaging studies, shedding light on disease mechanisms and treatment responses with unparalleled precision and clarity.
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