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Fmoc-Cystamine hydrochloride

  CAS No.: 2893917-85-4   Cat No.: BADC-02027   Purity: >98% 4.5  

Fmoc-Cystamine hydrochloride can be used as an ADC linker. It is a cleavable linker that can be reduced under reducing conditions to release the payload. This type of linker is useful for creating ADCs that can selectively release their cytotoxic payload in the reducing environment of cells, thereby minimizing off-target effects.

Fmoc-Cystamine hydrochloride

Structure of 2893917-85-4

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ADC Linker
Molecular Formula
C19H23ClN2O2S2
Molecular Weight
410.98
Storage
Store at 2-8 °C

* For research and manufacturing use only. We do not sell to patients.

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Synonyms
(9H-Fluoren-9-yl)methyl N-{2-[(2-azaniumylethyl)disulfanyl]ethyl}carbamate chloride; mono-Fmoc-cystamine hydrochloride; 2-((9-Fluorenylmethyloxycarbonylamino)ethyl)disulfanyl-(2-aminoethane) hydrochloride; Fmoc-SS-NH2 HCl; (9H-Fluoren-9-yl)methyl 2-((2-aminoethyl)disulfanyl)ethylcarbamate hydrochloride; Fmoc-Cystamine.HCl; Fmoc-Cystamine HCl
IUPAC Name
9H-fluoren-9-ylmethyl N-[2-(2-aminoethyldisulfanyl)ethyl]carbamate;hydrochloride
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCSSCCN.Cl
InChI
InChI=1S/C19H22N2O2S2.ClH/c20-9-11-24-25-12-10-21-19(22)23-13-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18;/h1-8,18H,9-13,20H2,(H,21,22);1H
InChIKey
MWPQGKMRSXDIDT-UHFFFAOYSA-N
Melting Point
132-137 °C
Appearance
White crystalline powder
Storage
Store at 2-8 °C

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Fmoc-L-Lys(N3-Gly)-OH | Poc-AEEA DCHA | MC-betaglucuronide-MMAE-2 | Poc-AEEA | CCK2R Ligand-Linker Conjugates 1 | N3-DAPr-Suc-OH | Seco-Duocamycin GA | Thalidomide-NH-PEG7 | Azidoethyl-SS-ethylamine hydrochloride | Tr-PEG5-OH | Fmoc-Cystamine hydrochloride
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