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DBCO-NH-PEG4-maleimide

CAS No.: 1480516-75-3

Cat No.: BADC-00956

Purity: >98.0% 4.5

DBCO-NH-PEG4-maleimide is a heterobifunctional ADC linker combining maleimide thiol-reactivity and DBCO for SPAAC click chemistry, facilitating versatile and stable antibody-drug conjugate formation.

DBCO-NH-PEG4-maleimide

Structure of 1480516-75-3

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Category

ADC Linker

Molecular Formula

C36H42N4O9

Molecular Weight

674.74

Shipping

-20°C (International: -20°C)

Shipping

Store at -20 °C, keep in dry and avoid sunlight.

* For research and manufacturing use only. We do not sell to patients.

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Delivery of 200+ ADCs annually;
mg to g scale for early stage;
4,000 m² cGMP facilities;
CDMO and CMO support.

24/7 customer service;
100% quality assurance;
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Over 95% customer satisfaction.

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Synonyms

DBCO-PEG4-Maleimide;DBCO-NH-PEG4-Maleimide; DBCO-PEG4-MAL

IUPAC Name

N-[2-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-(2,5-dioxopyrrol-1-yl)propanamide

Canonical SMILES

C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCNC(=O)CCOCCOCCOCCOCCNC(=O)CCN4C(=O)C=CC4=O

InChI

InChI=1S/C36H42N4O9/c41-32(14-18-39-34(43)11-12-35(39)44)38-17-20-47-22-24-49-26-25-48-23-21-46-19-15-33(42)37-16-13-36(45)40-27-30-7-2-1-5-28(30)9-10-29-6-3-4-8-31(29)40/h1-8,11-12H,13-27H2,(H,37,42)(H,38,41)

InChIKey

VVFZXPZWVJMYPX-UHFFFAOYSA-N

Density

1.3±0.1 g/cm3

Solubility

10 mm in DMSO

Flash Point

537.6±34.3 °C

Index Of Refraction

1.616

Vapor Pressure

0.0±0.3 mmHg at 25°C

Appearance

Solid

Shelf Life

-20°C 3 years powder; -80°C 2 years in solvent

Shipping

-20°C (International: -20°C)

Storage

Store at -20 °C, keep in dry and avoid sunlight.

Boiling Point

965.2±65.0 °C at 760 mmHg

Form

Solid

Biological Activity

DBCO-PEG4-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Catalog	Product Name	CAS	Inquiry
BADC-00909	DBCO-NH-PEG4-amine	1255942-08-5

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