Azido-PEG5-alcohol

  Cat No.: BADC-01172   Purity: >98.0% 4.5  

Azido-PEG5-alcohol is a PEG-containing bioorthogonal conjugation building block that provides an azide handle for modular click-chemistry workflows. The molecule can be used to introduce a click-reactive group onto an antibody, peptide, linker intermediate, or payload-containing component, depending on the chemistry of its second terminal functionality. Its additional reactive group is azide bioorthogonal handle; requires complementary click handle on the antibody. The structure includes peg5 spacer to provide hydrophilic spacing. Conjugation can be performed using spaac with dbco/bcn-functionalized partner or cuaac with terminal alkyne partner, depending the complementary handle. The sequence and orientation of the coupling steps should be selected according to the functional groups carried by the two conjugation partners.

Azido-PEG5-alcohol

Structure of 86770-68-5

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Category
ADC Linker
Molecular Formula
C10H21N3O5
Molecular Weight
263.29
Shipping
Room temperature
Storage
Store at -20 °C, keep in dry and avoid sunlight.

* For research and manufacturing use only. We do not sell to patients.

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Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Synonyms
14-Azido-3,6,9,12-tetraoxatetradecanol; 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethanol
IUPAC Name
2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethanol
SMILES
C(COCCOCCOCCOCCO)N=[N+]=[N-]
InChI
InChI=1S/C10H21N3O5/c11-13-12-1-3-15-5-7-17-9-10-18-8-6-16-4-2-14/h14H,1-10H2
InChIKey
JTGGTGKXQQGEHB-UHFFFAOYSA-N
Solubility
10 mm in DMSO
PSA
106.90000
Appearance
Colorless to light orange to yellow clear liquid
Shelf Life
≥ 2 years
Shipping
Room temperature
Storage
Store at -20 °C, keep in dry and avoid sunlight.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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