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CHO-Ph-CONH-PEG3-NHS ester is a non-cleavable 3-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs).
Structure of 2101206-32-8
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Popular Publications Citing BOC Sciences Products
2,5-Dioxopyrrolidin-1-yl 3-[2-(2-{2-[(4-formylphenyl)formamido]ethoxy}ethoxy)ethoxy]propanoate, commonly known as a key intermediate in organic synthesis, holds significant value in the development of pharmaceuticals. One major application is its role in the preparation of potent antagonist or agonist molecules for various receptors. Its unique chemical structure allows for the easy introduction of formyl groups, which can be further manipulated to synthesize a diverse range of pharmacologically active compounds. This ability to serve as a versatile building block makes it an essential component in medicinal chemistry for drug design and discovery.
Another critical application of 2,5-dioxopyrrolidin-1-yl 3-[2-(2-{2-[(4-formylphenyl)formamido]ethoxy}ethoxy)ethoxy]propanoate is in the field of bioconjugation. This compound is particularly valuable in the conjugation of biomolecules such as proteins, peptides, and antibodies. By facilitating the linkage of these biomolecules to various probes or therapeutic agents, it enhances their functional properties and stability. This application is especially vital in the development of targeted drug delivery systems and diagnostic tools, where precision and efficiency are paramount.
In materials science, 2,5-dioxopyrrolidin-1-yl 3-[2-(2-{2-[(4-formylphenyl)formamido]ethoxy}ethoxy)ethoxy]propanoate is utilized in the synthesis of advanced polymeric materials. Its role as a cross-linking agent in the formation of hydrogels, coatings, and other polymeric structures is indispensable. These modified materials exhibit improved mechanical properties, stability, and responsiveness to environmental stimuli, which are crucial for applications in biomedical implants, sensors, and smart materials. This contributes to the development of next-generation materials with enhanced performance and durability.
Lastly, this compound is instrumental in the field of chemical biology, particularly in the study of biological pathways and mechanisms. 2,5-Dioxopyrrolidin-1-yl 3-[2-(2-{2-[(4-formylphenyl)formamido]ethoxy}ethoxy)ethoxy]propanoate is often used in the synthesis of small molecule probes or inhibitors to dissect complex biological systems. By enabling the selective and covalent modification of specific biomolecules, researchers can investigate cellular processes with high precision. This application provides insights into disease mechanisms, facilitating the development of novel therapeutic strategies and enhancing our understanding of fundamental biological functions.
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