CHO-Ph-CONH-PEG3-NHS ester

  Cat No.: BADC-00644   Purity: ≥95% 4.5  

CHO-Ph-CONH-PEG3-NHS ester is a non-cleavable 3-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs).

CHO-Ph-CONH-PEG3-NHS ester

Structure of 2101206-32-8

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
ADC Linker
Molecular Formula
C21H26N2O9
Molecular Weight
450.44
Shipping
Room temperature, or blue ice upon request.
Storage
Store at 2-8°C

* For research and manufacturing use only. We do not sell to patients.

Size Price Stock Quantity
-- $-- In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

Popular Publications Citing BOC Sciences Products
Synonyms
Ald-Ph-amido-PEG3-NHS ester; Propanoic acid, 3-[2-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; N-{2-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethoxy]ethyl}-4-formylbenzamide; Benzamide, N-[2-[2-[2-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethyl]-4-formyl-; 2,5-Dioxopyrrolidin-1-yl 3-[2-(2-{2-[(4-formylphenyl)formamido]ethoxy}ethoxy)ethoxy]propanoate
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]ethoxy]propanoate
SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCNC(=O)C2=CC=C(C=C2)C=O
InChI
InChI=1S/C21H26N2O9/c24-15-16-1-3-17(4-2-16)21(28)22-8-10-30-12-14-31-13-11-29-9-7-20(27)32-23-18(25)5-6-19(23)26/h1-4,15H,5-14H2,(H,22,28)
InChIKey
LFDQXMGOLAFWOQ-UHFFFAOYSA-N
Shipping
Room temperature, or blue ice upon request.
Storage
Store at 2-8°C

2,5-Dioxopyrrolidin-1-yl 3-[2-(2-{2-[(4-formylphenyl)formamido]ethoxy}ethoxy)ethoxy]propanoate, commonly known as a key intermediate in organic synthesis, holds significant value in the development of pharmaceuticals. One major application is its role in the preparation of potent antagonist or agonist molecules for various receptors. Its unique chemical structure allows for the easy introduction of formyl groups, which can be further manipulated to synthesize a diverse range of pharmacologically active compounds. This ability to serve as a versatile building block makes it an essential component in medicinal chemistry for drug design and discovery.

Another critical application of 2,5-dioxopyrrolidin-1-yl 3-[2-(2-{2-[(4-formylphenyl)formamido]ethoxy}ethoxy)ethoxy]propanoate is in the field of bioconjugation. This compound is particularly valuable in the conjugation of biomolecules such as proteins, peptides, and antibodies. By facilitating the linkage of these biomolecules to various probes or therapeutic agents, it enhances their functional properties and stability. This application is especially vital in the development of targeted drug delivery systems and diagnostic tools, where precision and efficiency are paramount.

In materials science, 2,5-dioxopyrrolidin-1-yl 3-[2-(2-{2-[(4-formylphenyl)formamido]ethoxy}ethoxy)ethoxy]propanoate is utilized in the synthesis of advanced polymeric materials. Its role as a cross-linking agent in the formation of hydrogels, coatings, and other polymeric structures is indispensable. These modified materials exhibit improved mechanical properties, stability, and responsiveness to environmental stimuli, which are crucial for applications in biomedical implants, sensors, and smart materials. This contributes to the development of next-generation materials with enhanced performance and durability.

Lastly, this compound is instrumental in the field of chemical biology, particularly in the study of biological pathways and mechanisms. 2,5-Dioxopyrrolidin-1-yl 3-[2-(2-{2-[(4-formylphenyl)formamido]ethoxy}ethoxy)ethoxy]propanoate is often used in the synthesis of small molecule probes or inhibitors to dissect complex biological systems. By enabling the selective and covalent modification of specific biomolecules, researchers can investigate cellular processes with high precision. This application provides insights into disease mechanisms, facilitating the development of novel therapeutic strategies and enhancing our understanding of fundamental biological functions.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Contact our experts today for pricing and comprehensive details on our ADC offerings.

You May Also Be Interested In

From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.

ADC Linker Development Enzyme Cleavable Linker Cathepsin B Cleavable Linker Phosphatase Cleavable Linker β-Glucuronide Linker β-Galactosidase Cleavable Linker Sulfatase Cleavable Linker Chemically Cleavable Linker Non-Cleavable Linker Services Acid Cleavable Linker

Unlock Deeper ADC Insights

Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.

Linkers - A Crucial Factor in Antibody–Drug Conjugates In-Depth Review of ADC Linkers: Types, Mechanisms, and Research Progress New Structural Insights Solve Instability Issues of Maleimide Linkers in ADCs PEG Linkers in Antibody-Drug Conjugates Peptide Linkers in Antibody-Drug Conjugates Disulfide Linkers in Antibody-Drug Conjugates Biotinylation Reagents in Antibody-Drug Conjugates Maleimide Linkers in Antibody-Drug Conjugates Current ADC Linker Chemistry SPDB Linkers in Antibody-Drug Conjugates

Explore More ADC Products

Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.

ADC Cytotoxin

Powerful Targeted Cancer Solutions

ADC  Cytotoxin with Linker

Enhanced Stability And Efficacy

ADC Linker

Precise Conjugation For Success

Antibody-Drug  Conjugates (ADCs)

Maximized Therapeutic Performance

Auristatins

Next-Level Tubulin Inhibition

Calicheamicins

High-Impact DNA Targeting

Camptothecins

Advanced Topoisomerase Inhibition

Daunorubicins / Doxorubicins

Trusted Anthracycline Payloads

Duocarmycins

Potent DNA Alkylation Agents

Maytansinoids

Superior Microtubule Disruption

Pyrrolobenzodiazepines

Ultra-Potent DNA Crosslinkers

Traditional Cytotoxic Agents

Proven Chemotherapy Solutions

Cleavable Linker

Precise Intracellular Drug Release

Non-Cleavable Linker

Exceptional Long-Term Stability

Historical Records: Val-Cit-PAB-MMAE TFA salt | MC-VC-PABC-MMAE | Ala-Ala-Asn-PAB TFA salt | MAC glucuronide linker-1 | DBA-DM4 | endo-BCN-PEG3-PFP ester | Ala-Ala-Asn-PAB | 2,5-Dioxopyrrolidin-1-yl 4-((2-(1,3-Dioxoisoindolin-2-Yl)ethyl)disulfanyl)butanoate | Azidoethyl-SS-ethylamine | (R)-2-Azido-3-(Fmoc-amino)propanoic acid | CHO-Ph-CONH-PEG3-NHS ester
Send Inquiry
Verification code
Inquiry Basket
loading Loading......
Go to checkout