Name: H-L-Lys(4-N3-Z)-OH HCl
Brand: BOC Sciences
Rating: 5 (1 reviews)

Synonyms

H-L-Lys(4-N3-Z)-OH.HCl; H-Lys(Z(4-N3))-OH.HCl; pAzZLys.HCl; H-Lys(Z-4-N3)-OH.HCl; (2S)-6-(4-Azido-benzyloxycarbonylamino)-2-amino-hexanoic acid hydrochloride; Nε-p-Azidobenzyloxycarbonyl lysine hydrochloride; PABK.HCl; H-Lys(4-N3-Z).HCl; H-Lys(4-N3-Z)-OH.HCl; N-epsilon-p-azidobenzyloxycarbonyl lysine hydrochloride; H-L-Lys(4-N3-Z)-OH hydrochloride; L-Lysine, N6-[[(4-azidophenyl)methoxy]carbonyl]-, hydrochloride (1:1); N6-(((4-Azidobenzyl)oxy)carbonyl)-L-lysine hydrochloride

IUPAC Name

(2S)-2-amino-6-[(4-azidophenyl)methoxycarbonylamino]hexanoic acid;hydrochloride

Canonical SMILES

C1=CC(=CC=C1COC(=O)NCCCC[C@@H](C(=O)O)N)N=[N+]=[N-].Cl

InChI

InChI=1S/C14H19N5O4.ClH/c15-12(13(20)21)3-1-2-8-17-14(22)23-9-10-4-6-11(7-5-10)18-19-16;/h4-7,12H,1-3,8-9,15H2,(H,17,22)(H,20,21);1H/t12-;/m0./s1

InChIKey

AQUASNYNCOKBBC-YDALLXLXSA-N

Appearance

White to light yellow solid

Storage

Store at 2-8 °C

H-L-Lys(4-N3-Z)-OH hydrochloride, a peptide with diverse biochemical and pharmacological uses, finds application in various fields. Here are four key ways this product is applied:

Peptide Synthesis: Serving as a pivotal building block in peptide synthesis, H-L-Lys(4-N3-Z)-OH hydrochloride facilitates the creation of intricate peptide structures. Its integration allows for the design of peptides with specific sequences and functional groups, playing a crucial role in generating tailored peptides for research purposes. Scientists leverage this compound to investigate protein-protein interactions, enzyme activity, and receptor binding, unraveling the complexities of molecular interactions within biological systems.

Drug Development: Positioned at the forefront of pharmaceutical innovation, H-L-Lys(4-N3-Z)-OH hydrochloride drives the development of peptide-based therapeutics. Peptides synthesized using this compound can be engineered for enhanced stability, specificity, and efficacy, shaping the landscape of drug discovery. It plays an indispensable role in formulating potent drug candidates for a spectrum of ailments, ranging from cancer and diabetes to autoimmune disorders.

Bioconjugation: Embraced in bioconjugation endeavors, H-L-Lys(4-N3-Z)-OH hydrochloride acts as a linchpin in linking peptides to various entities like fluorophores, drugs, or nanoparticles. This conjugation strategy fosters the creation of targeted delivery systems and diagnostic tools, propelling advancements in precision medicine. Researchers harness these conjugates for diverse applications, including imaging, therapeutic targeting, and biosensing.

Structural Biology: In the realm of structural biology, H-L-Lys(4-N3-Z)-OH hydrochloride emerges as a key component in fabricating peptide substrates or inhibitors for crystallography studies. These peptides play a pivotal role in elucidating the three-dimensional configurations of proteins and their interactions with ligands, shedding light on the molecular basis of biological functions.

Catalog	Product Name	CAS
BADC-01714	H-L-Lys(N3-Gly)-OH	1198617-82-1
BADC-01733	H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride	2560614-20-0
BADC-01882	H-L-Lys(N3-Gly)-OH hydrochloride