H-L-Lys(4-N3-Z)-OH hydrochloride - CAS 2084913-49-3

H-L-Lys(4-N3-Z)-OH hydrochloride - CAS 2084913-49-3 Catalog number: BADC-01820

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H-L-Lys(4-N3-Z)-OH hydrochloride is a click chemistry reagent containing an azide group. It is an infrared probe and a photo-affinity reagent.

Category
ADCs Linker
Product Name
H-L-Lys(4-N3-Z)-OH hydrochloride
CAS
2084913-49-3
Catalog Number
BADC-01820
Molecular Formula
C14H20ClN5O4
Molecular Weight
357.79

Ordering Information

Catalog Number Size Price Quantity
BADC-01820 -- $-- Inquiry
Description
H-L-Lys(4-N3-Z)-OH hydrochloride is a click chemistry reagent containing an azide group. It is an infrared probe and a photo-affinity reagent.
IUPAC Name
(2S)-2-amino-6-[(4-azidophenyl)methoxycarbonylamino]hexanoic acid;hydrochloride
Canonical SMILES
C1=CC(=CC=C1COC(=O)NCCCCC(C(=O)O)N)N=[N+]=[N-].Cl
InChI
InChI=1S/C14H19N5O4.ClH/c15-12(13(20)21)3-1-2-8-17-14(22)23-9-10-4-6-11(7-5-10)18-19-16;/h4-7,12H,1-3,8-9,15H2,(H,17,22)(H,20,21);1H/t12-;/m0./s1
InChIKey
AQUASNYNCOKBBC-YDALLXLXSA-N
Appearance
White to Light Yellow Solid

H-L-Lys(4-N3-Z)-OH hydrochloride, a peptide with diverse biochemical and pharmacological uses, finds application in various fields. Here are four key ways this product is applied:

Peptide Synthesis: Serving as a pivotal building block in peptide synthesis, H-L-Lys(4-N3-Z)-OH hydrochloride facilitates the creation of intricate peptide structures. Its integration allows for the design of peptides with specific sequences and functional groups, playing a crucial role in generating tailored peptides for research purposes. Scientists leverage this compound to investigate protein-protein interactions, enzyme activity, and receptor binding, unraveling the complexities of molecular interactions within biological systems.

Drug Development: Positioned at the forefront of pharmaceutical innovation, H-L-Lys(4-N3-Z)-OH hydrochloride drives the development of peptide-based therapeutics. Peptides synthesized using this compound can be engineered for enhanced stability, specificity, and efficacy, shaping the landscape of drug discovery. It plays an indispensable role in formulating potent drug candidates for a spectrum of ailments, ranging from cancer and diabetes to autoimmune disorders.

Bioconjugation: Embraced in bioconjugation endeavors, H-L-Lys(4-N3-Z)-OH hydrochloride acts as a linchpin in linking peptides to various entities like fluorophores, drugs, or nanoparticles. This conjugation strategy fosters the creation of targeted delivery systems and diagnostic tools, propelling advancements in precision medicine. Researchers harness these conjugates for diverse applications, including imaging, therapeutic targeting, and biosensing.

Structural Biology: In the realm of structural biology, H-L-Lys(4-N3-Z)-OH hydrochloride emerges as a key component in fabricating peptide substrates or inhibitors for crystallography studies. These peptides play a pivotal role in elucidating the three-dimensional configurations of proteins and their interactions with ligands, shedding light on the molecular basis of biological functions.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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