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CAS No.:
Cat No.: BADC-01208
Purity: >98.0%
4.5 
Amino-bis-PEG3-TCO is a bifunctional ADC linker with TCO moieties enabling dual site-specific click conjugations, improving payload loading and pharmacokinetics in antibody-drug conjugates.
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Amino-bis-PEG3-TCO is a versatile bifunctional linker molecule used in bioconjugation and drug delivery systems. Here are some key applications of Amino-bis-PEG3-TCO:
Site-Specific Bioconjugation: Amino-bis-PEG3-TCO allows for the precise attachment of biomolecules to specific sites on proteins or antibodies. This specificity is essential for creating highly functional and stable conjugates used in therapeutic and diagnostic applications. The bifunctional nature of Amino-bis-PEG3-TCO enhances the effectiveness of targeted delivery systems.
Drug Delivery: Amino-bis-PEG3-TCO is leveraged in the development of advanced drug delivery systems. By linking drugs to the molecule, precise delivery to target tissues and cells can be achieved, minimizing off-target effects and enhancing therapeutic efficacy. The PEGylation aspect of the linker improves the solubility and reduces the immunogenicity of the drug conjugates.
Diagnostic Imaging: In diagnostic applications, Amino-bis-PEG3-TCO facilitates the conjugation of imaging agents to specific biomarkers. This targeted conjugation improves the accuracy and sensitivity of imaging techniques such as PET, MRI, and fluorescence imaging. As a result, tumor localization, disease monitoring, and biodistribution studies become more reliable.
Biosensor Development: Amino-bis-PEG3-TCO is used in creating biosensors by linking recognition elements, such as antibodies or peptides, to sensor surfaces. This enables the detection of specific analytes with high sensitivity and specificity. The flexibility and stability provided by the PEG spacer improve the performance of biosensors in various analytical applications.
| Catalog | Product Name | CAS | Inquiry |
|---|---|---|---|
| BADC-01207 | Amino-bis-PEG3-DBCO | ||
| BADC-01206 | Amino-bis-PEG3-BCN |
Amino-bis-PEG3-TCO
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Amino-bis-PEG3-TCO
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