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Acid-C3-SSPy

  CAS No.: 250266-79-6   Cat No.: BADC-01509 4.5  

Acid-C3-SSPy is a cleavable disulfide-containing ADC linker with pyridyl disulfide and carboxylic acid groups, enabling site-specific thiol conjugation and redox-sensitive drug release.

Acid-C3-SSPy

Structure of 250266-79-6

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ADC Linker
Molecular Formula
C9H11NO2S2
Molecular Weight
229.32

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Synonyms
4-(2-pyridyldithio)butanoic acid; 4-(pyridin-2-yldisulfanyl)butanoic acid; Acid-C3-SSPy
IUPAC Name
Canonical SMILES
C1=CC=NC(=C1)SSCCCC(=O)O
InChI
InChI=1S/C9H11NO2S2/c11-9(12)5-3-7-13-14-8-4-1-2-6-10-8/h1-2,4,6H,3,5,7H2,(H,11,12)
InChIKey
SLMVEZKWNOGJPD-UHFFFAOYSA-N
Pictograms
Corrosive; Irritant
Signal Word
Danger

Acid-C3-SSPy, a versatile compound with multifaceted applications in the realm of bioscience, showcases a diverse array of uses. Here are four key applications presented with high perplexity and burstiness:

Bioconjugation: An indispensable technique in molecular biology, Acid-C3-SSPy plays a pivotal role in bioconjugation processes, linking biomolecules through enduring covalent bonds. This intricate procedure lies at the core of crafting targeted drug delivery systems and cutting-edge diagnostic tools. By conjugating antibodies, peptides, or other ligands, researchers can forge precision therapeutics and sophisticated biosensors, advancing the frontiers of medical research.

Protein Labeling: At the forefront of protein biology, Acid-C3-SSPy emerges as a dependable agent for labeling proteins with fluorescent dyes or other discernible tags. This application is crucial for scrutinizing protein localization, interactions, and dynamics within cellular or in vitro settings. Enhanced visualization and quantification of proteins deepen our comprehension of cellular mechanisms and disease pathways, shedding light on the intricate dance of biological molecules.

Surface Modification: Venturing into the realm of material science, Acid-C3-SSPy finds its niche in functionalizing surfaces of nanoparticles, polymers, and diverse materials. This modification gives rise to biofunctional surfaces, capable of specific interactions with biological targets. Such surfaces are instrumental in the development of biosensors, diagnostic assays, and scaffolds for tissue engineering, bridging the realms of biology and material engineering with finesse.

Drug Delivery Systems: In the realm of pharmaceutical innovation, Acid-C3-SSPy takes center stage in designing advanced drug delivery systems, acting as a versatile linker or spacer molecule. By tethering therapeutic agents to Acid-C3-SSPy-modified carriers, researchers gain precise control over drug release and targeting to specific tissues. This tailored approach enhances treatment efficacy while minimizing side effects, heralding a new era of personalized medicine and targeted therapies.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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