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THP-SS-PEG1-Tos

  CAS No.: 1807512-37-3   Cat No.: BADC-00999   Purity: >98.0% 4.5  

THP-SS-PEG1-Tos is a tosylate-activated, disulfide PEG linker facilitating cleavable conjugation in antibody-drug conjugates, enhancing payload release and linker stability under physiological conditions.

THP-SS-PEG1-Tos

Structure of 1807512-37-3

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Category
ADC Linker
Molecular Formula
C16H24O5S3
Molecular Weight
392.55
Shipping
Room temperature, or blue ice upon request.
Shipping
Store at -20 °C, keep in dry and avoid sunlight.

* For research and manufacturing use only. We do not sell to patients.

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Popular Publications Citing BOC Sciences Products
Synonyms
2-((2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)disulfanyl)ethyl 4-methylbenzenesulfonate
IUPAC Name
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)OCCSSCCOC2CCCCO2
InChI
InChI=1S/C16H24O5S3/c1-14-5-7-15(8-6-14)24(17,18)21-11-13-23-22-12-10-20-16-4-2-3-9-19-16/h5-8,16H,2-4,9-13H2,1H3
InChIKey
WJDBLPWPLQRBJB-UHFFFAOYSA-N
Density
1.3±0.1 g/cm3
Solubility
10 mm in DMSO
Flash Point
280.0±30.1 °C
Index Of Refraction
1.586
Vapor Pressure
0.0±1.4 mmHg at 25°C
Appearance
Solid
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
Room temperature, or blue ice upon request.
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Boiling Point
539.4±50.0 °C at 760 mmHg
Form
Solid

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Historical Records: Methyltetrazine-PEG4-aldehyde | Anetumab ravtansine | Maytansinoid B | Fmoc-PEG4-NHS ester | t-Boc-N-amido-PEG7-alcohol | m-PEG8-COOH | γ-Amanitin | 5-Maleimidovaleric acid | Boc-NH-ethyl-SS-propionic acid | Fmoc-NH-ethyl-SS-propionic acid | THP-SS-PEG1-Tos
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