Name: DBCO-S-S-acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

Synonyms

DBCO-S-S-acid

IUPAC Name

Canonical SMILES

C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCC(=O)NCCSSCCC(=O)O

InChI

InChI=1S/C24H24N2O4S2/c27-22(25-14-16-32-31-15-13-24(29)30)11-12-23(28)26-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)26/h1-8H,11-17H2,(H,25,27)(H,29,30)

InChIKey

PEZSNNGHQIWOEV-UHFFFAOYSA-N

DBCO-S-S-acid, a bio-orthogonal reagent renowned for its key role in chemical biology, brings forth a realm of applications centered on site-specific conjugation and bioconjugation. Here are four pivotal applications of DBCO-S-S-acid:

Protein Labeling: Widely embraced in the realm of protein labeling, DBCO-S-S-acid empowers researchers to affix fluorescent tags or diverse functional groups onto specific amino acids in proteins. This facilitates the tracking of protein localization, interactions, and dynamics within cellular landscapes. The bio-orthogonal essence of DBCO-S-S-acid ensures that the labeling process seamlessly coexists with the natural functionality of the protein, unveiling new dimensions in cellular exploration.

Drug Delivery: Pioneering the development of targeted drug delivery systems, DBCO-S-S-acid emerges as a pivotal player in conjugating therapeutic compounds to precision-targeting molecules like antibodies or ligands. This strategic coupling ensures the delivery of drugs exclusively to afflicted cells, amplifying therapeutic efficacy while minimizing potential side effects. The steadfast and modifiable characteristics of the disulfide bond enable controlled drug release at the designated target site.

Bioimaging: Positioned at the forefront of bioimaging endeavors, DBCO-S-S-acid emerges as a cornerstone in the conjugation of imaging agents to vital biomolecules. This fusion catalyzes the visualization of intricate cellular processes and enables precise imaging of specific tissues or organs within live organisms. With its unparalleled specificity and capacity to generate distinct signals, DBCO-S-S-acid stands as an indispensable tool for cutting-edge diagnostic and research applications.

Surface Functionalization: In the spheres of material science and bioengineering, DBCO-S-S-acid reigns supreme in surface modification through the integration of bioactive molecules. This augmentation enhances the biocompatibility and functionality of diverse materials, signifying a pivotal advancement in the realm of bioengineering. By anchoring enzymes or antibodies onto sensor surfaces, DBCO-S-S-acid elevates the sensitivity and selectivity of biosensors, propelling the development of state-of-the-art diagnostic tools and innovative biointerfaces that redefine the boundaries of scientific exploration.