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bisSP1

  CAS No.: 2253947-15-6   Cat No.: BADC-01632 4.5  

bisSP1 is an antibody agent conjugates linker. bisSP1 is a click chemistry reagent, and it contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups.

bisSP1

Structure of 2253947-15-6

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ADC Linker
Molecular Formula
C12H23N9O2
Molecular Weight
325.37

* For research and manufacturing use only. We do not sell to patients.

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Synonyms
di-azide amine Linker
IUPAC Name
(2S)-6-amino-2-(3-azidopropanoylamino)-N-(3-azidopropyl)hexanamide
Canonical SMILES
C(CCN)CC(C(=O)NCCCN=[N+]=[N-])NC(=O)CCN=[N+]=[N-]
InChI
InChI=1S/C12H23N9O2/c13-6-2-1-4-10(19-11(22)5-9-18-21-15)12(23)16-7-3-8-17-20-14/h10H,1-9,13H2,(H,16,23)(H,19,22)/t10-/m0/s1
InChIKey
LRQNLHXWGRMZJY-JTQLQIEISA-N
Appearance
White to Off-white Solid

bisSP1 is a synthetic peptide with versatile roles in biomedical research and clinical applications. Here are some key applications of bisSP1:

Cancer Therapy: bisSP1 has shown potential as a therapeutic agent in cancer treatment by targeting specific tumor cells. It can induce apoptosis in cancerous cells while sparing normal healthy cells. This selective action makes bisSP1 a promising candidate for reducing tumor growth and improving the efficacy of existing cancer therapies.

Drug Delivery Systems: bisSP1 can be utilized as a targeting moiety in drug delivery systems, enhancing the precision and efficiency of drug delivery to diseased tissues. By conjugating bisSP1 to nanoparticles or other drug carriers, the modified systems can selectively home in on target cells, increasing the therapeutic index and reducing systemic side effects. This application is particularly instrumental in developing personalized medicine approaches.

Diagnostic Imaging: bisSP1 can be used as a contrast agent in diagnostic imaging, aiding in the visualization of specific tissues and pathological conditions. When labeled with radiotracers or fluorescent markers, bisSP1 can help in the early detection and monitoring of diseases such as cancer and inflammatory conditions. This can lead to more accurate diagnoses and timely interventions.

Tissue Engineering: bisSP1 plays a role in promoting tissue regeneration and repair, which is vital in healing injuries and developing tissue-engineered grafts. It can enhance cell proliferation and differentiation, contributing to the formation of functional tissues. Incorporating bisSP1 into scaffolds and biomaterials can improve their bioactivity and integration with host tissue.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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