Aminooxy-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-C2-PEG3-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Structure of 1306615-51-9
* For research and manufacturing use only. We do not sell to patients.
Size | Price | Stock | Quantity |
---|---|---|---|
-- | $-- | In stock |
Looking for different specifications? Click to request a custom quote!
Capabilities & Facilities
Aminooxy-PEG3-azide, a versatile chemical linker widely employed in bioconjugation and crosslinking, finds diverse applications in the following areas represented with heightened perplexity and burstiness:
Bioconjugation: Leveraging Aminooxy-PEG3-azide for bioconjugation purposes fosters the coupling of proteins, peptides, and other biomolecules with exceptional precision. This compound facilitates site-specific conjugation via oxime ligation, ensuring robust and effective attachment mechanisms. Such conjugations play a pivotal role in crafting targeted drug delivery systems and diagnostic tools, revolutionizing the realms of biomedicine.
Click Chemistry: Positioned as a cornerstone reagent in click chemistry, Aminooxy-PEG3-azide plays a pivotal role in catalyzing azide-alkyne cycloaddition reactions, particularly in the presence of copper. This dynamic enables the swift and selective formation of triazoles, expediting the synthesis of intricate molecules. Widely embraced in medicinal chemistry, material science, and nanotechnology, this technology drives innovation and complexity in various scientific domains.
Surface Modification: Unveiling its prowess in surface modification, Aminooxy-PEG3-azide emerges as a transformative tool for functionalizing diverse substrates like glass, nanoparticles, and polymers. By immobilizing biomolecules on these surfaces, researchers cultivate bioactive interfaces tailored for biosensors, bioassays, and tissue engineering endeavors. This breakthrough underscores significant progress in diagnostic platforms and biomedical devices, propelling the frontier of biotechnological advancements.
Drug Delivery: Within the realm of drug delivery, Aminooxy-PEG3-azide assumes a critical role in crafting drug conjugates and delivery vehicles engineered for precision and efficacy. The incorporation of the PEG linker enhances drug solubility and stability, while the azide group provides a platform for further functionalization. This strategic approach fortifies targeted drug delivery mechanisms, amplifying the therapeutic potential and efficacy of pharmaceutical agents.
Catalog | Product Name | CAS | Inquiry |
---|---|---|---|
BADC-00877 | Aminooxy-PEG2-azide | 1043426-13-6 |
Contact our experts today for pricing and comprehensive details on our ADC offerings.
From cytotoxin synthesis to linker design, discover our specialized services that complement your ADC projects.
Learn more about payload design, linker strategies, and integrated CDMO support through our curated ADC content.
Find exactly what your project needs from our expanded range of ADCs, offering flexible options to fit your timelines and goals.