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Non-cleavable

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Catalog Product Name CAS Number
BADC-01955 m-PEG10-COOH 2409969-94-2
m-PEG10-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01959 Methyltetrazine-amino-PEG3-CH2CH2NHBoc 2141976-32-9
Methyltetrazine-amino-PEG3-CH2CH2NHBoc is a heterobifunctional PEG linker. Inquiry
BADC-01952 m-PEG11-COOH 2280998-74-3
m-PEG11-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01960 Methyltetrazine-amino-PEG4-CH2CH2NHBoc 2143955-71-7
Methyltetrazine-amino-PEG4-CH2CH2NHBoc is a heterobifunctional PEG linker. Inquiry
BADC-01919 Boc-D-trans-Hyp-OH 147266-92-0
Boc-D-trans-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Inquiry
BADC-01961 Methyltetrazine-amino-PEG8-CH2CH2NHBoc 2143968-21-0
Methyltetrazine-amino-PEG8-CH2CH2NHBoc is a heterobifunctional PEG linker containing a methyltetrazine group and a protected amino group. The methyltetrazine group is reactive with carboxylic acids and activated esters via click chemistry. Inquiry
BADC-01958 Methyltetrazine-amino-PEG8-CH2CH2NHMal 2143968-05-0
Methyltetrazine-amino-PEG8-CH2CH2NHMal is a heterobifunctional PEG linker cintaining a methyltetrazine group and a maleimide group. The methyltetrazine group is reactive with carboxylic acids and activated esters via click chemistry, and the maleimide group can react with the thiol group in biomolecules. Inquiry
BADC-00368 N-[gamma-Maleimidobutyryloxy]sulfo-succinimide ester 158018-81-6
N-[gamma-Maleimidobutyryloxy]sulfo-succinimide ester is a highly significant and versatile compound that plays a pivotal role in the realm of biomedicine. Specifically designed for the purpose of labeling and conjugating biomolecules, this remarkable product has garnered immense attention in the field. Its wide-ranging applications span the development of targeted therapies, imaging agents, and drug delivery systems. By virtue of its maleimide group, which exhibits exceptional specificity, it empowers researchers to precisely target sulfhydryl-containing proteins or antibodies, thereby rendering feasible the treatment of an array of diseases, including but not limited to cancer or autoimmune disorders. Inquiry
BADC-00503 N-Succinimidyl 4-(N-maleimidomethyl) trans-cyclohexane 1-carboxylate 71875-81-5
N-Succinimidyl 4-(N-maleimidomethyl) trans-cyclohexane 1-carboxylate is an essential compound in the biomedical sector that exhibits high complexity and variability in its applications. Acting as a reactive linker, it facilitates the conjugation of biomolecules to proteins, peptides, or drugs, thereby enabling targeted therapeutic delivery for addressing diverse ailments including cancer and autoimmune disorders. Embracing this compound empowers the biomedical industry to explore innovative means of combating diseases. Inquiry
BADC-01343 DOTA-NHS-ester TFA Salt 2832911-57-4
DOTA-NHS-ester TFA Salt is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. It can be used to label radiotherapeutic agents or imaging probes for the detection of tumors. Inquiry
BADC-01931 Methyl 1-Cbz-azetidine-3-carboxylate 757239-60-4
Methyl 1-Cbz-azetidine-3-carboxylate is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker. Inquiry
BADC-01531 Cyclooctyne-O-amido-PEG4-NHS ester 2101206-50-0
Cyclooctyne-O-amido-PEG4-NHS ester is a key reagent used in the biomedical industry for the efficient conjugation of biological molecules. It enables the site-specific modification of proteins, peptides, and antibodies for various applications such as drug delivery, diagnostics, and targeted therapy. This NHS ester derivative offers high stability and reactivity, making it suitable for the synthesis of bioconjugates used in the treatment of diseases like cancer and autoimmune disorders. Inquiry
BADC-01532 Cyclooctyne-O-amido-PEG3-NHS ester 2101206-34-0
Cyclooctyne-O-amido-PEG3-NHS ester is a valuable compound used in the biomedical industry for bioconjugation purposes. It acts as a versatile crosslinker for labeling and modification of biomolecules, such as proteins and antibodies. With its NHS ester functionality, it enables efficient and stable conjugation to primary amines. It finds applications in drug delivery systems, diagnostics, and targeted therapeutics, contributing to advancements in treating various diseases. Inquiry
BADC-01533 Cyclooctyne-O-amido-PEG2-NHS ester 2101206-22-6
Cyclooctyne-O-amido-PEG2-NHS ester is a highly versatile biomedical product extensively employed in the domains of bioconjugation and pharmaceutical transport. It showcases its adeptness as a reactive connector, thus expediting the conjugation of amine-infused entities with biomolecular components. Its cutting-edge composition exhibits remarkable utility in the realm of targeted pharmaceutical transport frameworks, antibody-drug conjugates, as well as bioimaging technologies, thereby augmenting the therapeutic approaches for an array of afflictions encompassing cancer and inflammatory disorders. Inquiry
BADC-01636 Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br 2344809-82-9
Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br is an ADC linker that can be used to synthesize ABBV-154, ABBV-927, ABBV-368 or their analogs. Inquiry
BADC-01640 XMT-1519 conjugate-1 2720500-19-4
XMT-1519 conjugate-1 is a linker for the HER-2 monoclonal antibody XMT-1519. XMT-1519 can be used to synthesize ADC and increase anti-tumor activity. Inquiry
BADC-01649 Indole-C2-amide-C2-NH2 215789-29-0
A potent linker. Inquiry
BADC-01661 Gly-Gly-Gly-PEG2-azide 2222277-20-3
Gly-Gly-Gly-PEG2-azide is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01664 Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 2244602-35-3
Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 is a branched linker that can be used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01666 Macropa-NCS 2146095-31-8
Macropa-NCS can be coupled with antibodies to form tumor-selective carrier molecules, which can be further combined with radionuclides as specific targeting cancer cell carriers, and is a linker-chelating agent in targeted alpha research (TAT). Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070. Inquiry
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