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Non-Cleavable Linker
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Non-Cleavable Linker

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Catalog Product Name CAS Number
BADC-00692 DNP-PEG4-NHS ester 858126-78-0
DNP-PEG4-NHS ester is a PEG linker containing a DNP moiety and an NHS ester terminal group. DNP is involved in biological applications such as involvement in ion transport across membranes. The NHS ester can react with primary amines to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. Inquiry
BADC-00693 t-boc-N-amido-PEG4-NHS ester 859230-20-9
t-Boc-N-amido-PEG4-NHS ester is a PEG derivative containing an NHS ester and a Boc-protected amino group. The Boc group can be deprotected under mild acidic conditions to form the free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. PEG Linkers may be useful in the development of antibody drug conjugates. Inquiry
BADC-00699 mPEG6-CH2CH2COONHS ester 874208-92-1
mPEG6-CH2CH2COONHS ester is a bifunctional PEG linker combining an NHS ester with a PEG6 chain. It enables efficient amine-reactive conjugation in ADC design, improving hydrophilicity and stability of antibody-drug conjugates for targeted therapeutic delivery. Inquiry
BADC-00700 mPEG4-CH2CH2COONHS ester 874208-94-3
mPEG4-CH2CH2COONHS ester provides a shorter PEG4 spacer with an NHS ester reactive group, facilitating controlled conjugation to antibody amines. It enhances solubility and stability in ADC payload attachment and bioconjugation applications. Inquiry
BADC-00701 4-formylphenyl 3-iodo-4-methoxybenzoate 875107-50-9
4-formylphenyl 3-iodo-4-methoxybenzoate acts as a reactive ADC linker with aldehyde and iodoaryl groups, allowing site-specific conjugation and stable payload attachment in antibody-drug conjugates for enhanced targeted therapy. Inquiry
BADC-00702 m-PEG3-NHS ester 876746-59-7
m-PEG3-NHS ester is a reactive ADC linker combining a PEG3 spacer with an NHS ester group. It enables efficient amine-targeted conjugation, enhancing payload attachment and linker stability in advanced antibody-drug conjugate synthesis and development. Inquiry
BADC-00703 6-O-2-Propyn-1-yl-D-galactose 881895-59-6
6-O-2-Propyn-1-yl-D-galactose is a nonclaevable glycolinker for the functionalization of cytotoxic drugs and applications in antibody-drug conjugation. Inquiry
BADC-00705 (2,5-dioxopyrrolidin-1-yl) 4-(methyldisulfanyl)butanoate 905449-92-5
(2,5-dioxopyrrolidin-1-yl) 4-(methyldisulfanyl)butanoate is a cleavable ADC linker featuring disulfide and NHS ester groups, facilitating stable conjugation and controlled intracellular payload release for improved ADC efficacy. Inquiry
BADC-00706 (2,5-dioxopyrrolidin-1-yl) 5-[[3-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-4-nitrocyclohexyl]disulfanyl]-2-nitrobenzoate 924898-35-1
(2,5-dioxopyrrolidin-1-yl) 5-[[3-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-4-nitrocyclohexyl]disulfanyl]-2-nitrobenzoate is a linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00713 Mal-PEG3-PFP ester 1807534-78-6
Mal-PEG3-PFP ester is a PEG linker containing maleimide and PFP moieties. Maleimide is thiol-reactive and reacts between pH 6.5 and 7.5 to form thiol ester bonds. PFP moiety is amine-reactive and is less susceptible to undergoing hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media. Inquiry
BADC-00874 Maleimide-DOTA 1006711-90-5
Maleimide-DOTA is a bifunctional linker used in ADCs and radiopharmaceuticals. It combines a maleimide group for thiol-reactive conjugation with DOTA, a chelator for radiometal labeling. This makes it suitable for imaging-guided drug delivery and therapeutic antibody conjugates. Inquiry
BADC-00877 Aminooxy-PEG2-azide 1043426-13-6
Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-00878 mPEG6-azide 1043884-49-6
mPEG6-azide is a mid-length PEG ADC linker featuring azide functionality for copper-free click chemistry, improving solubility and biocompatibility in antibody-drug conjugates. Inquiry
BADC-00879 PEG12-Tos 1050500-41-8
PEG12-Tos offers a long PEG12 chain with tosylate functionality, providing high solubility and flexible linker length. It's widely used in ADC linker chemistry for improved conjugation efficiency and stability in antibody-drug conjugate manufacturing. Inquiry
BADC-00880 Tr-PEG2-OH 105589-77-3
Tr-PEG2-OH is a PROTAC linker (belonging to the PEG class) that can be used to synthesize PROTAC molecules. Tr-PEG2-OH is also a non-cleavable 2-unit PEG ADC linker that is used in the synthesis of antibody-conjugated drugs (ADCs). Inquiry
BADC-00881 Azido-PEG3-acid 1056024-94-2
Azido-PEG3-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-00882 m-PEG5-succinimidyl carbonate 1058691-00-1
m-PEG5-succinimidyl carbonate is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-00883 mPEG7-aldehyde 1058691-77-2
mPEG7-aldehyde is a PEG linker featuring an aldehyde group for site-selective oxime or hydrazone ligation in ADC assembly. Its PEG7 spacer enhances solubility and flexibility, supporting stable and targeted antibody-drug conjugation. Inquiry
BADC-00885 Aminooxy-PEG4-alcohol 106492-60-8
Aminooxy-PEG4-alcohol is a non-cleavable 4-unit PEG ADC linker that is used in the synthesis of antibody conjugated drugs (ADCs). Aminooxy-PEG4-alcohol is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules. Inquiry
BADC-00889 m-PEG8-COOH 1093647-41-6
m-PEG8-COOH offers a longer PEG linker with terminal carboxylic acid functionality, facilitating controlled payload attachment in ADC synthesis. It improves hydrophilicity and stability of bioconjugates, enhancing pharmacokinetic profiles. Inquiry
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