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Non-Cleavable Linker
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Non-Cleavable Linker

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Catalog Product Name CAS Number
BADC-01937 (R)-(+) Azetidine-2-carboxylic acid 7729-30-8
(R)-(+) Azetidine-2-carboxylic acid is a rigid, cyclic amino acid ideal for stabilizing ADC linker frameworks. Its conformational constraints enhance spatial control in drug conjugates, making it a valuable intermediate for creating cleavable or non-cleavable linkers in site-specific bioconjugation strategies. Inquiry
BADC-01939 Methyl (2R,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylate 114676-69-6
Methyl (2R,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylate is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker. Inquiry
BADC-01943 FMOC-L-HYP(BOM)-OH 187223-15-0
FMOC-L-HYP(BOM)-OH is a dual-protected hydroxyproline used for constructing peptide-based ADC linkers with site-specific reactivity and enzymatic cleavage control. Inquiry
BADC-01944 Boc-D-trans-Hyp-Ome 135042-17-0
Boc-D-trans-Hyp-Ome is a stereochemically defined hydroxyproline derivative for constructing custom linkers in ADCs and bioconjugates. Useful in chiral linker design. Inquiry
BADC-01952 m-PEG11-COOH 2280998-74-3
m-PEG11-COOH is a long PEG linker used in ADC synthesis to increase hydrophilicity and improve pharmacokinetics, enhancing antibody-drug conjugate stability and therapeutic efficacy. Inquiry
BADC-01955 m-PEG10-COOH 2409969-94-2
m-PEG10-COOH is a hydrophilic PEG-based ADC linker intermediate featuring a 10-unit PEG spacer and carboxyl terminal. It enhances antibody solubility, improves conjugation efficiency, and provides stability for controlled drug release in antibody-drug conjugate development and targeted cancer therapy. Inquiry
BADC-01958 Methyltetrazine-amino-PEG8-CH2CH2NHMal 2143968-05-0
Methyltetrazine-amino-PEG8-CH2CH2NHMal is a heterobifunctional PEG linker cintaining a methyltetrazine group and a maleimide group. The methyltetrazine group is reactive with carboxylic acids and activated esters via click chemistry, and the maleimide group can react with the thiol group in biomolecules. Inquiry
BADC-01959 Methyltetrazine-amino-PEG3-CH2CH2NHBoc 2141976-32-9
Methyltetrazine-amino-PEG3-CH2CH2NHBoc provides a shorter PEG spacer ADC linker with methyltetrazine functionality, facilitating efficient and selective antibody conjugation in ADC synthesis. Inquiry
BADC-01960 Methyltetrazine-amino-PEG4-CH2CH2NHBoc 2143955-71-7
Methyltetrazine-amino-PEG4-CH2CH2NHBoc is a protected ADC linker enabling selective bioorthogonal conjugation with enhanced stability for precision antibody-drug conjugate manufacturing. Inquiry
BADC-01961 Methyltetrazine-amino-PEG8-CH2CH2NHBoc 2143968-21-0
Methyltetrazine-amino-PEG8-CH2CH2NHBoc is a heterobifunctional PEG linker containing a methyltetrazine group and a protected amino group. The methyltetrazine group is reactive with carboxylic acids and activated esters via click chemistry. Inquiry
BADC-01962 Methyltetrazine-amino-PEG4-amine 2055646-21-2
Methyltetrazine-amino-PEG4-amine is a versatile ADC linker offering rapid bioorthogonal conjugation and flexible amine functionality, ideal for custom antibody-drug conjugate construction. Inquiry
BADC-01963 Octadecanedioic acid mono-tert-butyl ester 843666-40-0
Octadecanedioic acid mono-tert-butyl ester is used to engineer long-acting, potent exendin-4 based GLP-1 analog for microstructure-based transdermal delivery for glycemic control. Inquiry
BADC-01975 Fmoc-Lys(Pal-Glu-OtBu)-OH 1491158-62-3
Fmoc-Lys(Pal-Glu-OtBu)-OH is a non-cleavable ADC linker. It can also be used as an alkyl chain-based PROTAC linker. Inquiry
BADC-02016 t-Boc-aminooxy-PEG3-propargyl 1951439-46-5
t-Boc-aminooxy-PEG3-propargyl is a crosslinker containing a propargyl group and t-Boc-aminooxy group. t-Boc-aminooxy-PEG3-propargyl can be used as an ADC linker. Inquiry
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