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Non-Cleavable Linker
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Non-Cleavable Linker

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Catalog Product Name CAS Number
BADC-01014 Propargyl-PEG2-acid 1859379-85-3
Propargyl-PEG2-acid is an alkyne-functionalized PEG linker with a carboxylic acid group, supporting copper-free click chemistry in ADC construction. Its PEG2 spacer offers hydrophilicity and facilitates site-specific payload conjugation for enhanced therapeutic efficacy. Inquiry
BADC-01015 Hydroxy-PEG3-t-butyl ester 186020-66-6
Hydroxy-PEG3-t-butyl ester is a protected PEG linker offering hydroxyl functionality for downstream activation. Its t-butyl group ensures synthetic control, while the PEG3 spacer enhances solubility and biocompatibility in ADC linker and payload formulations. Inquiry
BADC-01024 Amino-PEG4-acetic acid 195071-49-9
Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01028 Ald-Ph-amido-PEG4-propargyl 1969299-27-1
Ald-Ph-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01032 m-PEG12-OH 2050595-03-2
m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01033 Fluorescein-DBCO 2054339-00-1
Fluorescein-DBCO is a fluorescent ADC linker combining DBCO for SPAAC click chemistry and fluorescein dye, enabling targeted drug delivery with real-time imaging capabilities. Inquiry
BADC-01045 Propargyl-PEG9-bromide 2055042-83-4
Propargyl-PEG9-bromide is a bifunctional ADC linker with an alkyne group for click reactions and bromide for nucleophilic substitution. Suitable for antibody-drug conjugate construction requiring extended PEG spacers. Inquiry
BADC-01046 Propargyl-PEG8-bromide 2055046-25-6
Propargyl-PEG8-bromide features a terminal alkyne and bromide for versatile conjugation chemistry. Its long PEG8 spacer enhances hydrophilicity and is suitable for use in ADC linker strategies. Inquiry
BADC-01060 Cyclooctyne-O-amido-PEG3-PFP ester 2101206-33-9
Cyclooctyne-O-amido-PEG3-PFP ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01061 Cyclooctyne-O-amido-PEG2-PFP ester 2101206-61-3
Cyclooctyne-O-amido-PEG2-PFP ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01085 MAC glucuronide linker-1 2222981-71-5
MAC glucuronide linker-1 is an enzyme-cleavable ADC linker designed for selective drug release in tumor microenvironments, enhancing targeted delivery and therapeutic efficacy in antibody-drug conjugates. Inquiry
BADC-01087 Mal-PEG3-C1-NHS ester 2230016-26-7
Mal-PEG3-C1-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01090 Boc-aminooxy-amide-PEG4-propargyl 2253965-01-2
Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01091 Aminooxy-amido-PEG4-propargyl 2253965-03-4
Aminooxy-amido-PEG4-propargyl is a non-cleavable 4-unit PEG ADC linker that can be used to synthesize antibody-conjugated drugs (ADCs). Inquiry
BADC-01106 Mal-PEG2-VCP-NB 2395887-69-9
Mal-PEG2-VCP-NB is a maleimide-activated ADC linker with valine-citrulline protease-cleavable sequence and nitrobenzyl group, designed for targeted intracellular drug release in antibody-drug conjugates. Inquiry
BADC-01109 Benzyl-PEG6-alcohol 24342-68-5
Benzyl-PEG6-alcohol is a PEGylated linker intermediate featuring a benzyl-protected end group. It enhances solubility, flexibility, and biocompatibility in ADC linker design and supports hydrophilic spacer integration for improved pharmacokinetics and reduced aggregation in antibody-drug conjugate systems. Inquiry
BADC-01113 mPEG10-alcohol 27425-92-9
m-PEG10-alcohol (Decaethylene glycol monomethyl ether) is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG10-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Inquiry
BADC-01117 Amino-PEG5-alcohol 34188-11-9
NH2-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG5-OH is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01120 SIA Crosslinker 39028-27-8
SIA Crosslinker is a heterobifunctional ADC linker featuring succinimidyl and iodoacetyl groups for targeted antibody modification, enabling stable and site-specific drug conjugation in ADC platforms. Inquiry
BADC-01122 Doxorubicin-SMCC 400647-59-8
Doxorubicin-SMCC is a pre-activated ADC linker-payload combining a cytotoxic agent with a maleimide NHS ester linker. Enables targeted drug delivery by conjugating with antibody thiol groups. Inquiry
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