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Non-Cleavable Linker
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Non-Cleavable Linker

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Catalog Product Name CAS Number
BADC-00928 Propargyl-PEG3-acid 1347760-82-0
Propargyl-PEG3-acid is an alkyne-functionalized ADC linker with a carboxyl terminus for amide coupling. Its PEG spacer enhances solubility and flexibility in antibody-drug conjugates, facilitating click chemistry-based bioconjugation strategies. Inquiry
BADC-00935 Biotin-PEG2-acid 1365655-89-5
Biotin-PEG2-acid combines a biotin tag with a short PEG linker, ideal for ADCs and affinity-based purification. It enables avidin-biotin interaction, facilitating antibody targeting, detection, or capture in bioconjugation and drug delivery applications. Inquiry
BADC-00936 Mal-PEG2-acid 1374666-32-6
Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule. Inquiry
BADC-00937 Aminoxyacetamide-PEG3-azide 1379761-16-6
Aminoxyacetamide-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-00938 mPEG10-amine 1383658-09-0
m-PEG10-amine is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG10-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Inquiry
BADC-00947 Tr-PEG5-OH 141282-24-8
Tr-PEG5-OH is a PROTAC linker (belonging to the PEG class) that can be used to synthesize PROTAC molecules. Tr-PEG5-OH is also a non-cleavable 5-unit PEG ADC linker that is used in the synthesis of antibody-conjugated drugs (ADCs). Inquiry
BADC-00948 DBCO-C6-acid 1425485-72-8
DBCO-C6-acid is a carboxylic acid-functionalized ADC linker featuring dibenzocyclooctyne for copper-free click conjugation, enhancing biocompatibility and site-specific antibody modification. Inquiry
BADC-00949 Azido-PEG5-propionic acid 1425973-16-5
Azido-PEG5-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-00953 Ald-CH2-PEG5-azide 1446282-38-7
Ald-CH2-PEG5-azide is a bifunctional ADC linker intermediate featuring an aldehyde and azide group separated by a PEG5 spacer, enabling dual conjugation via click chemistry and Schiff base formation for precise payload attachment in antibody-drug conjugates. Keywords: ADC linker, bifunctional linker, aldehyde, azide, PEG spacer, click chemistry. Inquiry
BADC-00954 mPEG6-NHS ester 1449390-12-8
mPEG6-NHS ester is a PEG linker with a reactive NHS ester group used for amine coupling in ADC synthesis. The PEG6 spacer increases hydrophilicity, ensuring stable payload conjugation and improved pharmacokinetic behavior of antibody-drug conjugates. Inquiry
BADC-00967 Propargyl-PEG5-amine 1589522-46-2
Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Inquiry
BADC-00975 mPEG5-acetic acid 16142-03-3
mPEG5-acetic acid serves as a key PEG linker component in ADC synthesis, enhancing hydrophilicity and stability of antibody-drug conjugates for efficient therapeutic payload attachment and controlled release. Inquiry
BADC-00983 Azido-PEG2-amine 166388-57-4
Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG2-C2-amine is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-00984 Azido-PEG9-acid 1670249-37-2
Azido-PEG9-acid is an extended PEG-based ADC linker enabling efficient click chemistry conjugation, enhancing solubility and targeted drug delivery in antibody-drug conjugates. Inquiry
BADC-00987 DOTA-NHS-ester 170908-81-3
DOTA-NHS-ester is a widely used bifunctional linker in ADCs and radiolabeled antibody design. It combines an NHS ester for amine coupling with a DOTA chelator for radiometal complexation. Ideal for therapeutic and diagnostic conjugates requiring site-specific labeling. Inquiry
BADC-00992 Azide-PEG3-Tos 178685-33-1
Azide-PEG3-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azide-PEG3-Tos is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-00994 Methyltetrazine-DBCO 1802238-48-7
Methyltetrazine-DBCO is a heterobifunctional ADC linker enabling fast, selective dual click chemistry reactions (IEDDA and SPAAC), enhancing conjugation efficiency in antibody-drug conjugate production. Inquiry
BADC-00996 N-(5-Hydroxypentyl)maleimide 180608-78-0
N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) ). Inquiry
BADC-01006 Bis-PEG1-PFP ester 1807539-02-1
Bis-PEG1-PFP ester is a bifunctional PEG-based NHS ester ADC linker enabling efficient amine-reactive conjugation at two sites, improving ADC flexibility and targeted payload delivery. Inquiry
BADC-01012 Aminooxy-PEG2-alcohol 185022-12-2
Aminooxy-PEG2-alcohol is a non-cleavable 2-unit PEG ADC linker that is used in the synthesis of antibody conjugated drugs (ADCs). Aminooxy-PEG2-alcohol is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules. Inquiry
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