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Non-Cleavable Linker
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Non-Cleavable Linker

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Catalog Product Name CAS Number
BADC-00567 4-Formyl-N-(2-(naphthalen-2-Yloxy)ethyl)benzamide 1228153-04-5
4-Formyl-N-(2-(naphthalen-2-Yloxy)ethyl)benzamide is an aromatic aldehyde ADC linker enabling site-specific antibody conjugation, improving antibody-drug conjugate payload stability and tumor targeting. Inquiry
BADC-00568 1-((4-((2-(2-(7-Amino-4-Methyl-1-Oxo-1H-Isochromen-3-Yl)acetamido)ethyl)disulfanyl)butanoyl)oxy)-2,5-Dioxopyrrolidine-3-Sulfonic Acid 1246497-13-1
1-((4-((2-(2-(7-Amino-4-methyl-1-oxo-1H-isochromen-3-yl)acetamido)ethyl)disulfanyl)butanoyl)oxy)-2, 5-dioxopyrrolidine-3-sulfonic acid is a linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00570 2,5-Dioxopyrrolidin-1-Yl 3-(2,4-Di-Tert-Pentylphenoxy)propanoate 124709-46-2
2,5-Dioxopyrrolidin-1-Yl 3-(2,4-Di-Tert-Pentylphenoxy)propanoate is an NHS ester ADC linker that promotes efficient antibody conjugation through phenolic groups, enhancing payload stability and ADC therapeutic performance. Inquiry
BADC-00571 t-Boc-N-amido-PEG1-NHS ester 1260092-55-4
t-Boc-N-amido-PEG1-NHS ester is a PEG linker containing NHS ester and Boc-protected amine moieties. The Boc group can be deprotected under mildly acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media. Inquiry
BADC-00572 Bromoacetamido-PEG4-NHS ester 1260139-70-5
Bromoacetamido-PEG4-NHS ester is a PEG derivative containing a bromide group and an NHS ester. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Bromoacetamido-PEG4-NHS ester is a PEGn linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00573 NHS-PEG(5)-CO-OBzl 1263044-84-3
NHS-PEG(5)-CO-OBzl is a PEGylated NHS ester ADC linker facilitating stable and flexible antibody conjugation with improved solubility and pharmacokinetic profiles in ADC therapies. Inquiry
BADC-00577 2,5-Dioxopyrrolidin-1-Yl 1-Bromo-3-Methyl-2-Oxo-6,9,12,15-Tetraoxa-3-Azaoctadecan-18-Oate 1283658-70-7
2, 5-Dioxopyrrolidin-1-yl 1-bromo-3-methyl-2-oxo-6, 9, 12, 15-tetraoxa-3-azaoctadecan-18-oate is a linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00578 BrCH2CONH-PEG8-NHS ester 1283658-79-6
BrCH2CONH-PEG8-NHS ester is a PEG linker containing a bromide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Inquiry
BADC-00579 (E)-2,5-Dioxopyrrolidin-1-Yl 17-Bromo-4,7,10,13-Tetraoxaheptadec-15-En-1-Oate 1283658-84-3
(E)-2, 5-Dioxopyrrolidin-1-yl 17-bromo-4, 7, 10, 13-tetraoxaheptadec-15-en-1-oate is a PEGn linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00580 2,5-Dioxopyrrolidin-1-Yl 4-Methyl-4-((2-Methyl-5-Oxo-5-(2-(trimethylsilyl)ethoxy)pentan-2-Yl)disulfanyl)pentanoate 1286715-33-0
2, 5-Dioxopyrrolidin-1-yl 4-methyl-4-((2-methyl-5-oxo-5-(2-(trimethylsilyl)ethoxy)pentan-2-yl)disulfanyl)pentanoate is a linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00581 3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate 1311459-55-8
3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate is an activated acrylate ADC linker enabling Michael addition conjugation with antibodies, promoting stable and efficient payload attachment for improved antibody-drug conjugate efficacy. Inquiry
BADC-00583 mPEG9-NHS ester 1316189-13-5
m-PEG9-NHS ester is a PEG derivative containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media. m-PEG9-NHS ester is a linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00584 Mal-amido-PEG8-acid 1334177-86-4
Mal-amido-PEG8-acid is a PEG derivative containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. Inquiry
BADC-00589 N-Methyl-N-[(3-methyldithio)-1-oxopropyl]-L-alanine 138148-62-6
N-Methyl-N-[(3-methyldithio)-1-oxopropyl]-L-alanine, a microtubule inhibitor, is a PEG linker used in antibody-drug-conjugation (ADC). Inquiry
BADC-00597 Sulfo-SIAB sodium 144650-93-1
Sulfo-SIAB sodium is a water-soluble heterobifunctional linker featuring NHS ester and iodoacetyl groups. Widely used in ADCs, it enables amine-to-thiol crosslinking, forming stable thioether bonds. Its sulfonated structure improves solubility, ideal for aqueous-phase bioconjugation. Inquiry
BADC-00599 2,5-Dioxopyrrolidin-1-yl 3-((3-((3-(trityloxy)propanoyl)oxy)propanoyl)oxy)propanoate 145069-77-8
2, 5-Dioxopyrrolidin-1-yl 3-((3-((3-(trityloxy)propanoyl)oxy)propanoyl)oxy)propanoate is a linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00602 Mal-L-Dap(Boc)-OH 1491152-23-8
Mal-L-PA-NH-Boc is a maleimide-functionalized ADC linker with protected amine groups, ideal for cysteine-specific conjugation in antibody-drug conjugate development, ensuring precise and stable drug attachment. Inquiry
BADC-00603 Mal-PEG3-NHS ester 1537892-36-6
Mal-PEG3-NHS ester is a non-cleavable ADC linker containing the Maleimide group. It can be used to prepare antibody conjugated drugs (ADCs). Inquiry
BADC-00616 2,5-Dioxopyrrolidin-1-yl 3-Hydroxypropanoate 178106-34-8
2,5-Dioxopyrrolidin-1-yl 3-Hydroxypropanoate is an NHS ester ADC linker enabling efficient conjugation through hydroxyl groups, promoting stable antibody-payload linkage and enhanced drug release control in ADCs. Inquiry
BADC-00618 Mal-PEG4-VA 1800456-31-8
Mal-PEG4-VA is a noncleavable ADC linker containing a Maleimide group. Mal-PEG4-VA is used for making antibody-drug conjugate. Inquiry
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