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Non-Cleavable Linker
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Non-Cleavable Linker

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Catalog Product Name CAS Number
BADC-00628 MAL-Tri-EG-Osu 2055353-77-8
MAL-Tri-EG-Osu is a maleimide-based ADC linker featuring triethylene glycol units. It provides selective thiol conjugation, enabling stable and site-specific antibody-drug conjugate formation with improved pharmacokinetics and payload stability. Inquiry
BADC-00636 PDB-Pfp 2088570-81-2
PDB-Pfp is a pentafluorophenyl ester ADC linker with pyridyl disulfide, facilitating cleavable conjugation and controlled intracellular drug release in antibody-drug conjugates. Inquiry
BADC-00638 NHPI-PEG3-C2-NHS ester 2101206-14-6
NHPI-PEG3-C2-NHS ester extends PEG2 to PEG3 spacer length, optimizing linker flexibility and conjugation kinetics. It serves as an efficient ADC linker for stable payload attachment and enhanced antibody-drug conjugate pharmacodynamics. Inquiry
BADC-00639 Ald-Ph-amido-PEG3-C2-Pfp ester 2101206-21-5
Ald-Ph-amido-PEG3-C2-Pfp ester is a PEGn linker for antibody-drug-conjugation (ADC). Ald-Ph-amido-PEG3-C2-Pfp ester is an noncleavable ADC linker, which belongs to a polyethylene glycol (PEG) linker. Inquiry
BADC-00642 Propargyl-O-C1-amido-PEG2-C2-NHS ester 2101206-30-6
Propargyl-O-C1-amido-PEG2-C2-NHS ester combines alkyne functionality with PEG2 spacer and NHS ester, enabling click chemistry and amine-targeted payload conjugation. It supports precise and stable antibody-drug conjugate assembly. Inquiry
BADC-00643 NHPI-PEG2-C2-NHS ester 2101206-31-7
NHPI-PEG2-C2-NHS ester is a highly reactive ADC linker intermediate with PEG2 spacer and N-hydroxyphthalimide activation. It facilitates selective payload attachment, enhancing antibody-drug conjugate synthesis efficiency and linker stability. Inquiry
BADC-00644 CHO-Ph-CONH-PEG3-NHS ester 2101206-32-8
CHO-Ph-CONH-PEG3-NHS ester is a non-cleavable 3-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Inquiry
BADC-00646 PDdB-Pfp 2101206-44-2
PDdB-Pfp is a disulfide-containing pentafluorophenyl ester linker for ADCs, enabling stable, cleavable payload attachment through thiol-exchange and amine coupling chemistry. Inquiry
BADC-00647 Mal-amide-PEG3-CH2 NHS ester 2101206-45-3
Mal-amide-PEG3-CH2 NHS ester is a heterobifunctional ADC linker offering maleimide and NHS ester groups for selective antibody conjugation and improved linker flexibility in drug conjugates. Inquiry
BADC-00648 NHPI-PEG4-C2-PFP ester 2101206-46-4
NHPI-PEG4-C2-PFP ester is a non-cleavable 4-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Inquiry
BADC-00649 NHPI-PEG2-C2-PFP ester 2101206-47-5
NHPI-PEG2-C2-PFP ester is a PEGylated NHS ester ADC linker intermediate facilitating efficient amine-reactive conjugation, improving solubility and site-specific payload attachment in ADC synthesis. Inquiry
BADC-00652 Ald-Ph-amido-PEG2-C2-Pfp ester 2101206-60-2
Ald-Ph-amido-PEG2-C2-Pfp ester is a PEGylated aldehyde-based ADC linker, facilitating bioorthogonal conjugation with antibodies, enhancing solubility and targeted payload delivery in ADCs. Inquiry
BADC-00654 Ald-Ph-amido-PEG1-C2-Pfp ester 2101206-67-9
Ald-Ph-amido-PEG1-C2-Pfp ester serves as a short PEG spacer ADC linker with aldehyde functionality, enabling site-specific conjugation and enhanced pharmacokinetics in antibody-drug conjugate design. Inquiry
BADC-00656 CHO-Ph-CONH-PEG1-NHS ester 2101206-80-6
CHO-Ph-CONH-PEG1-NHS ester features a short PEG1 linker with aldehyde and NHS ester groups, enabling versatile dual conjugation through oxime and amine chemistry. This ADC linker improves payload attachment flexibility and conjugate stability. Inquiry
BADC-00658 NHPI-PEG3-C2-PFP ester 2101206-87-3
NHPI-PEG3-C2-PFP ester offers a longer PEG spacer for enhanced flexibility in antibody conjugation, enabling improved pharmacokinetics and stability in antibody-drug conjugates. Inquiry
BADC-00659 Propargyl-O-C1-amido-PEG4-C2-NHS ester 2101206-92-0
Propargyl-O-C1-amido-PEG4-C2-NHS ester is an alkyne-terminated PEGylated ADC linker enabling bioorthogonal click chemistry conjugation. It enhances antibody-drug conjugate stability and payload delivery in targeted cancer therapies. Inquiry
BADC-00663 (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate 216145-65-2
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate is a PEGn linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00664 2,5-dioxopyrrolidin-1-yl 3-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)oxy)propanoate 221553-42-0
2,5-dioxopyrrolidin-1-yl 3-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)oxy)propanoate is a linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00672 MAC glucuronide linker 2260960-07-2
MAC glucuronide linker is a vital tool used in the biomedical industry for drug discovery and targeted therapy. It enables the conjugation of drugs with glucuronide, facilitating their delivery and activation in specific organs or tissues. This linker plays a significant role in treating various diseases, including cancer, inflammation, and metabolic disorders. Inquiry
BADC-00683 mPEG3-CH2CH2COONHS ester 622405-78-1
m-PEG4-NHS ester is a PEG derivative containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media. Inquiry
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