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Non-Cleavable Linker
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Non-Cleavable Linker

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Catalog Product Name CAS Number
BADC-00504 5-Maleimidovalericacid-NHS 103750-03-4
5-Maleimidovalericacid-NHS is a widely used bioconjugation reagent in the biomedical field, which can modify molecules such as proteins and peptides by establishing long-lasting amide bonds. This facilitates the creation of targeted medication management and diagnostic tools. Inquiry
BADC-00505 6-Maleimidocaproic acid sulfo-NHS 103848-61-9
6-Maleimidocaproic acid sulfo-NHS is a small molecule reagent used in the biomedical industry. It is commonly used to modify biomolecules, such as proteins and antibodies, for site-specific conjugation. This compound enables the efficient and stable attachment of drugs, tags, or targeting moieties to these biomolecules, thereby facilitating the development of innovative treatments for a variety of diseases, including cancer and autoimmune diseases. Inquiry
BADC-00506 GMBS 80307-12-6
GMBS is a non-cleavable linker widely used in antibody-drug conjugation development. Its unparalleled efficacy stems from its chemical cross-linking ability, promoting the covalent binding of proteins, peptides, antibodies and countless other molecules. Notably, GMBS occupies a key position in the fields of drug delivery systems, diagnostics, and evolving bioconjugation technologies. Inquiry
BADC-00507 N-Hydroxysuccinimidyl-4-azidobenzoate 53053-08-0
N-Hydroxysuccinimidyl-4-azidobenzoate is a non-cleavable linker in the field of antibody drug conjugation and has been widely used in the field of bioconjugation and cross-linking. Its key role is to facilitate the development of targeted drug delivery systems and diagnostic tools of paramount importance. By creating covalent bonds between biomolecules and multiple agents or interfaces, it provides a way to precisely target and manage diseases such as cancer, autoimmune abnormalities, and infectious diseases. Inquiry
BADC-00508 SPDPH 158913-22-5
SPDPH is a biochemical product used in cancer drug development. It acts as a linker moiety for attaching biomolecules to surfaces or to each other. The product plays a key role in drug delivery systems, cancer diagnostics and targeted therapies. SPDPH enables the targeted delivery of drugs and diagnostics, thereby increasing the efficacy and specificity of cancer treatments. Inquiry
BADC-00509 MTS-4-NHS 690632-55-4
MTS-4-NHS is a bifunctional ADC linker combining NHS ester and thiol-reactive methanethiosulfonate (MTS) groups. It enables efficient amine-thiol conjugation, widely used in developing cleavable, disulfide-based antibody-drug conjugates for controlled drug delivery. Inquiry
BADC-00512 m-PEG1-NHS ester 1027371-75-0
m-PEG1-NHS ester is a PEG derivative containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media. m-PEG1-NHS ester is a linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00513 (2S,2'S)-Bis(2,5-Dioxopyrrolidin-1-yl) 4,4'-Disulfanediylbis(2-Acetamidobutanoate) 102814-00-6
(2S, 2'S)-Bis(2, 5-dioxopyrrolidin-1-yl)4, 4'-disulfanediylbis(2-acetamidobutanoate) is a linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00514 2-(2-(2-(3-((2,5-Dioxopyrrolidin-1-yl)oxy)-3-Oxopropoxy)ethoxy)ethoxy)ethyl Acrylate 1042435-35-7
2-(2-(2-(3-((2, 5-Dioxopyrrolidin-1-yl)oxy)-3-oxopropoxy)ethoxy)ethoxy)ethyl acrylate is a PEG linker for antibody-drug-conjugation (ADC). Inquiry
BADC-00515 2,5-Dioxopyrrolidin-1-yl 2,5,7,10-Tetraoxatridecan-13-Oate 1053657-02-5
2,5-Dioxopyrrolidin-1-yl 2,5,7,10-Tetraoxatridecan-13-Oate is an NHS ester PEGylated ADC linker that improves solubility and flexibility. It supports efficient antibody conjugation and controlled payload release in antibody-drug conjugates. Inquiry
BADC-00516 Sulfo-SIAB 106145-13-5
Sulfo-SIAB is a water-soluble heterobifunctional ADC linker with NHS ester and iodoacetyl groups, enabling selective antibody conjugation and stable drug attachment in targeted therapies. Inquiry
BADC-00517 4-Formyl-N-(2-Isopropoxyethyl)benzamide 1061567-05-2
4-Formyl-N-(2-Isopropoxyethyl)benzamide is an aldehyde-functionalized ADC linker facilitating site-specific antibody conjugation, optimizing targeted drug delivery in antibody-drug conjugates. Inquiry
BADC-00518 AcS-PEG8-NHS 1070798-99-0
AcS-PEG8-NHS contains an acetyl-protected thiol and an amine-reactive N-hydroxysuccinimide (NHS) ester. Although it is commonly used for proteins, it is also suitable for any small molecules or peptides with suitable functionalities. Inquiry
BADC-00519 m-PEG2-NHS ester 1127247-34-0
m-PEG2-NHS ester is a short PEG-based NHS ester ADC linker enabling efficient and stable amine-reactive antibody conjugation, improving solubility and biocompatibility in ADC synthesis. Inquiry
BADC-00520 2,5-Dioxopyrrolidin-1-yl 3-(benzyloxy)propanoate 1134280-63-9
2,5-Dioxopyrrolidin-1-yl 3-(benzyloxy)propanoate is an NHS ester ADC linker facilitating conjugation via hydroxyl groups. The benzyloxy moiety enhances hydrophobic interactions, improving payload stability in antibody-drug conjugates. Inquiry
BADC-00521 2,5-Dioxopyrrolidin-1-yl 3-((2-Fluorobenzyl)oxy)propanoate 1134280-64-0
2,5-Dioxopyrrolidin-1-yl 3-((2-Fluorobenzyl)oxy)propanoate is an NHS ester-based ADC linker intermediate featuring fluorobenzyl moieties for enhanced amine-reactive conjugation, enabling precise antibody-drug conjugate synthesis with improved stability and targeted payload delivery. Inquiry
BADC-00522 2,5-Dioxopyrrolidin-1-yl 3-((2,4-Difluorobenzyl)oxy)propanoate 1134280-65-1
2,5-Dioxopyrrolidin-1-yl 3-((2,4-Difluorobenzyl)oxy)propanoate is a fluorinated NHS ester ADC linker promoting selective antibody conjugation and enhanced metabolic stability for improved antibody-drug conjugate performance. Inquiry
BADC-00523 N-(2-(2-Chloroethoxy)ethyl)-4-Formylbenzamide 1137575-49-5
N-(2-(2-Chloroethoxy)ethyl)-4-Formylbenzamide is an aldehyde-functionalized ADC linker optimized for bioorthogonal conjugation, offering high specificity in antibody-drug conjugate development to enhance targeted delivery and controlled payload release. Inquiry
BADC-00524 Mal-Tetra-EG-Osu 1151762-45-6
Mal-Tetra-EG-Osu is a maleimide-activated PEG-based ADC linker that offers flexible conjugation through cysteine residues, improving drug solubility and targeting efficiency in antibody-drug conjugates. Inquiry
BADC-00525 Propanoic Acid,3-[(23-Mercapto-3,6,9,12,15,18,21-Heptaoxatricos-1-Yl)oxy], 2,5-Dioxo-1-Pyrrolidinyl Ester 1159006-15-1
Propanoic Acid, 3-[(23-mercapto-3, 6, 9, 12, 15, 18, 21-heptaoxatricos-1-yl)oxy], 2, 5-dioxo-1-pyrrolidinyl Ester is a PEGn linker for antibody-drug-conjugation (ADC). Inquiry
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