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Non-Cleavable Linker
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Non-Cleavable Linker

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Catalog Product Name CAS Number
BADC-01904 Me-Tet-PEG3-NH2
Me-Tet-PEG3-NH2 is a methyl-tetrazine ADC linker with PEG3 spacer and amine functionality, enabling efficient bioorthogonal click conjugation and improved payload stability in antibody-drug conjugates. Keywords: ADC linker, methyl-tetrazine, PEG spacer, amine linker, click chemistry. Inquiry
BADC-01914 Boc-azetidine-3-carboxylic acid 142253-55-2
Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01915 Methyl azetidine-3-carboxylate hydrochloride 100202-39-9
Methyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01917 L-4-trans-Hydroxyproline methyl ester hydrochloride 40216-83-9
H-Hyp-OMe hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Inquiry
BADC-01918 N-Boc-cis-4-hydroxy-L-proline 87691-27-8
N-Boc-cis-4-hydroxy-L-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Inquiry
BADC-01919 Boc-D-trans-Hyp-OH 147266-92-0
Boc-D-trans-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Inquiry
BADC-01920 Azetidine-3-carboxylic acid 36476-78-5
Azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Inquiry
BADC-01921 tert-Butyl Hydrogen Hexadecanedioate 843666-27-3
tert-Butyl Hydrogen Hexadecanedioate is a long-chain dicarboxylic acid intermediate often used in hydrophobic ADC linker design to modulate drug release and distribution. Inquiry
BADC-01923 Eicosanedioic acid 2424-92-2
Eicosanedioic acid is a long-chain dicarboxylic acid linker that provides hydrophobicity in ADC and lipid-based drug conjugates. It is often used to modulate membrane interaction, enhance drug retention, or incorporate fatty acid chains in linker designs for antibody-drug conjugates and delivery systems. Inquiry
BADC-01924 trans-4-Hydroxy-D-proline HCl 142347-81-7
trans-4-Hydroxy-D-proline HCl is an amino acid derivative used in constructing stable or cleavable ADC linkers, contributing to stereoselective drug conjugation strategies. Inquiry
BADC-01925 1-BOC-Azetidine-3-carboxylic acid methyl ester 610791-05-4
1-BOC-Azetidine-3-carboxylic acid methyl ester is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker. Inquiry
BADC-01926 H-D-trans-Hyp-OMe HCl 481704-21-6
H-D-trans-Hyp-OMe HCl is a hydroxyproline derivative commonly used as a structural component in ADC linkers. It enables stereoselective peptide bond formation and supports lysosomal enzyme-triggered release in antibody-drug conjugates, contributing to improved selectivity and bioavailability in targeted drug delivery systems. Inquiry
BADC-01927 Boc-L-4-trans-hydroxyproline methyl ester 74844-91-0
Boc-L-4-trans-hydroxyproline methyl ester is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker. Inquiry
BADC-01928 cis-4-Hydroxy-D-proline HCl 77449-94-6
cis-4-Hydroxy-D-proline HCl is used in ADC linker synthesis to introduce chiral and cleavable motifs. This hydroxyproline-based intermediate enables controlled enzymatic release and selective drug activation, supporting precise payload delivery in targeted cancer therapies and biopharmaceutical development. Inquiry
BADC-01929 N-Boc-cis-4-Hydroxy-D-proline 135042-12-5
N-Boc-cis-4-Hydroxy-D-proline is a stereochemically defined building block used in the synthesis of peptide-based ADC linkers. It introduces hydroxyl functionality for tailored linker architectures and controlled drug release, making it ideal for ADC payload conjugation, bioconjugate design, and enzymatically cleavable linker systems. Inquiry
BADC-01931 Methyl 1-Cbz-azetidine-3-carboxylate 757239-60-4
Methyl 1-Cbz-azetidine-3-carboxylate is a cyclic linker intermediate used in rigidifying ADC linkers or peptidomimetics, supporting improved payload control. Inquiry
BADC-01932 1-Cbz-azetidine-3-carboxylic acid 97628-92-7
1-Cbz-azetidine-3-carboxylic acid provides a protected amine for constrained linker synthesis. Useful in ADCs for enhancing chemical stability and spatial orientation. Inquiry
BADC-01933 Boc-cis-L-4-hydroxyproline methyl ester 102195-79-9
Boc-cis-L-4-hydroxyproline methyl ester is a protected amino acid derivative used in peptide-based linker synthesis for ADCs and site-specific drug conjugates. Inquiry
BADC-01935 Methyl (2R,4R)-4-hydroxypyrrolidine-2-carboxylate hydrochloride 114676-59-4
Methyl (2R,4R)-4-hydroxypyrrolidine-2-carboxylate hydrochloride is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker. Inquiry
BADC-01936 ethyl azetidine-3-carboxylate hydrochloride 405090-31-5
ethyl azetidine-3-carboxylate hydrochloride is a versatile small-molecule scaffold for constrained linker development in ADCs and bioactive conjugates. Inquiry
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