Inquiry Basket
Catalog | Product Name | CAS Number |
---|---|---|
BADC-01388 | PROTAC BRD4 Degrader-10 | 2417370-49-9 |
PROTAC BRD4 Degrader-10, a PROTAC connected by ligands for von Hippel-Lindau and BRD4, can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with ... | Inquiry | |
BADC-01389 | PROTAC BRD4 Degrader-11 | |
PROTAC BRD4 Degrader-11 is a PROTAC linked by ligands for von Hippel-Lindau and BRD4. It is conjugated with STEAP1 and CLL1 antibodies to degrade BRD4 protein in PC3 prostate cancer cells with DC50s o... | Inquiry | |
BADC-01390 | PROTAC BRD4 Degrader-13 | 2417370-71-7 |
PROTAC BRD4 Degrader-13, a PROTAC connected by ligands for von Hippel-Lindau and BRD4, can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with ... | Inquiry | |
BADC-01391 | Methotrexate monohydrate | 6745-93-3 |
Methotrexate monohydrate is a DHhF reductase inhibitor that inhibits the enzyme dihydrofolate reductase and DNA synthesis. Therefore it is used to treat various cancers. | Inquiry | |
BADC-01392 | 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-9-methoxy-, (4S)- | 19685-10-0 |
Possess high anti-cancer properties. | Inquiry | |
BADC-01400 | Seco-DUBA | 1227961-59-2 |
seco-DUBA hydrochloride is a cell-permeable pro-drug that is cleaved into the active toxin (DUBA) in intracellular lysosomes by proteases, after internalization. The payload then alkylates the DNA, ca... | Inquiry | |
BADC-01401 | DGN462 | 1394079-41-4 |
DGN462 is a potent DNA alkylating agent with antitumor activity, such as against acute myeloid leukemia (AML). DGN462 can be used as an ADC toxin molecule to synthesize ADC. | Inquiry | |
BADC-01436 | DC44 | 1354787-77-1 |
DC44, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44 can be used for the targeted treatment of cancer. | Inquiry | |
BADC-01437 | Tolytoxin | 127999-44-4 |
Tolytoxin, a bioactive metabolite from cyanobacteria, is a potent antifungal antibiotic, exhibiting MICs of 0.25-8 nmol. Tolytoxin is a cyanobacterial macrolide that targets actin by inhibition of its... | Inquiry | |
BADC-01440 | Dxd-D5 | |
Dxd-D5 (Exatecan-D5 derivative for ADC) is a tritiated version of Dxd. Dxd is a potent DNA topoisomerase I inhibitor with IC50 of 0.31 μM, which can be used as a payload of an antibody drug-conjugated... | Inquiry | |
BADC-01441 | sulfo-DGN462 sodium | 1401203-09-5 |
sulfo-DGN46 sodium can be degraded to DGN462 in culture medium and plasma. DGN462 is a potent DNA alkylating agent with antitumor activity, such as against acute myeloid leukemia (AML). | Inquiry | |
BADC-01443 | 7-Aminomethyl-10-methyl-11-fluoro camptothecin | 2378616-23-8 |
7-Aminomethyl-10-methyl-11-fluoro camptothecin is a toxin molecule of MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158, compound 21a), which can be used to synthesize camp... | Inquiry | |
BADC-01444 | MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin | 2414594-29-7 |
MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a) is a camptothecin payload that can be conjugated with a monoclonal antibody (mAb) to synthesize a camptothecin antibod... | Inquiry | |
BADC-01445 | Methotrexate-d3 | 432545-63-6 |
Methotrexate-d3 is the deuterated version of Methotrexate. Methotrexate (Amethopterin) is an antimetabolite and antifolate that inhibits dihydrofolate reductase, which prevents the conversion of folat... | Inquiry | |
BADC-01447 | Paclitaxel D5 | 1129540-33-5 |
Paclitaxel D5 is deuterium-labeled paclitaxel. Paclitaxel is a natural antineoplastic agent that stabilizes tubulin aggregation. | Inquiry | |
BADC-01477 | PF-06380101 D8 | |
PF-06380101 D8 (Aur0101 D8) is the deuterated version of PF-06380101. PF-06380101 is an Auristatin microtubule inhibitor, a cytotoxic Dolastatin 10 analogue. | Inquiry | |
BADC-01478 | D8-MMAF | |
D8-MMAF hydrochloride is the deuterated form of MMAF hydrochloride. MMAF Hydrochloride is a potent tubulin polymerization inhibitor used as a cytotoxic component of antineoplastic drugs and antibody d... | Inquiry | |
BADC-01479 | 7-MAD-MDCPT | 765871-81-6 |
7-MAD-MDCPT, a camptothecin analog, is the active moiety in an antibody drug conjugate (ADC). | Inquiry | |
BADC-01486 | Dimethyl-SGD-1882 | |
Dimethyl-SGD-1882 (Dimethyl-PBD dimer) is a highly efficient DNA alkylator (DNA alkylator), which can be used as the toxin moiety of antibody drug conjugate (ADC). PBD Dimer is a DNA alkylating agent ... | Inquiry | |
BADC-01617 | ADC toxin 1 | 723340-57-6 |
ADC toxin 1 is an ADC cytotoxin with anti-cancer activities. ADC toxin 1 is against HCT-116 and PSN1 cells growth with both IC50 values of 0.86 µM. | Inquiry |