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Catalog | Product Name | CAS Number |
---|---|---|
BADC-01118 | Azidoethyl-SS-ethylazide | 352305-38-5 |
Azidoethyl-SS-ethylazide is a bifunctional cleavable ADC linker featuring azide and disulfide groups, enabling bioorthogonal conjugation and redox-sensitive drug release in targeted therapeutics. | Inquiry | |
BADC-01119 | Fmoc-Gly-Gly-OH | 35665-38-4 |
Fmoc-Gly-Gly-OH is a dipeptide linker component commonly used in cleavable ADC linker systems. Its small, flexible structure enables lysosomal enzyme-triggered cleavage, making it ideal for use in cytotoxic drug release applications within antibody-drug conjugates and other bioconjugates. | Inquiry | |
BADC-01121 | Amino-PEG6-alcohol | 39160-70-8 |
Amino-PEG6-alcohol is a bifunctional PEG linker with terminal amine and alcohol groups, commonly used in ADC synthesis to improve solubility and flexibility. Its PEG6 spacer aids in stable conjugation and enhances pharmacokinetics of antibody-drug conjugates. | Inquiry | |
BADC-01124 | Fmoc-N-amido-PEG4-acetic acid | 437655-95-3 |
Fmoc-N-amido-PEG4-acetic acid is a PEG linker intermediate with an Fmoc protecting group, used for stepwise ADC linker synthesis. The PEG4 spacer improves hydrophilicity and flexibility, aiding in controlled payload conjugation and antibody modification. | Inquiry | |
BADC-01126 | m-PEG7-Ms | 477775-57-8 |
m-PEG7-Ms is a mesylated monofunctional PEG linker offering high solubility and reactivity. Commonly used in ADCs, it serves as a spacer to improve pharmacokinetics of hydrophobic drugs. The mesyl group enables efficient substitution with amines, thiols, or other nucleophiles during linker modification. | Inquiry | |
BADC-01127 | Boc-Cystamine | 485800-26-8 |
Boc-Cystamine is a protected disulfide-containing ADC linker building block, enabling redox-sensitive payload attachment and site-specific antibody conjugation. | Inquiry | |
BADC-01128 | Boc-NH-ethyl-SS-propionic acid | 485800-27-9 |
Boc-NH-ethyl-SS-propionic acid is a cleavable ADC linker with Boc protection and disulfide bond, facilitating site-specific conjugation and controlled drug release in antibody-drug conjugates. | Inquiry | |
BADC-01131 | Maleimido-tri(ethylene glycol)-propionic acid | 518044-40-1 |
Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation. | Inquiry | |
BADC-01136 | Br-PEG4-COOtBu | 564476-32-0 |
Br-PEG4-COOtBu is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions. | Inquiry | |
BADC-01137 | Hydroxy-PEG3-SS-PEG3-alcohol | 5662-81-7 |
Hydroxy-PEG3-SS-PEG3-alcohol offers a cleavable PEGylated ADC linker with disulfide bonds and hydroxyl groups. This facilitates enhanced solubility and controlled drug release in antibody-drug conjugates, optimizing delivery in oncology applications. | Inquiry | |
BADC-01138 | 5-Maleimidovaleric acid | 57078-99-6 |
5-Maleimidovaleric acid is a thiol-reactive ADC linker commonly used to attach payloads to antibodies through maleimide–cysteine coupling. It offers excellent solubility and stability, supporting targeted drug delivery and selective release in tumor microenvironments. | Inquiry | |
BADC-01139 | N-Succinimidyl 3-(Bromoacetamido)propionate | 57159-62-3 |
N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | Inquiry | |
BADC-01141 | (2-pyridyldithio)-PEG4 acid | 581065-93-2 |
(2-pyridyldithio)-PEG4 acid is a cleavable ADC linker with pyridyldithiol for thiol-reactive conjugation and PEG spacer for solubility. Widely used in targeted antibody-drug conjugate design to improve payload stability and release. | Inquiry | |
BADC-01142 | Fmoc-N-amido-PEG5-acetic acid | 635287-26-2 |
Fmoc-N-amido-PEG5-acetic acid offers a longer PEG5 spacer with an Fmoc group, supporting advanced ADC linker synthesis. Its enhanced hydrophilicity and protecting group allow precise stepwise conjugation in antibody-drug conjugate production. | Inquiry | |
BADC-01143 | DMAC-PDB | 663599-04-0 |
DMAC-PDB is a potent ADC linker designed for stable payload attachment with optimized release profiles. It supports precise bioconjugation strategies in antibody-drug conjugates for enhanced therapeutic efficacy. | Inquiry | |
BADC-01144 | Amino-PEG4-propionic acid | 663921-15-1 |
Amino-PEG4-propionic acid is a medium-length PEG linker intermediate designed to improve antibody solubility and conjugation stability in ADCs. It enhances drug loading efficiency and supports controlled payload release for targeted therapies. | Inquiry | |
BADC-01146 | N-Butanoyl-L-homoserine lactone | 67605-85-0 |
N-Butanoyl-L-homoserine lactone is a signaling-mimetic compound used in linker design for controlled release in ADCs. Its lactone ring structure introduces enzymatically cleavable characteristics, allowing selective payload release in tumor microenvironments and enhancing therapeutic specificity. | Inquiry | |
BADC-01148 | Bis-Tos-(2-hydroxyethyl disulfide) | 69981-39-1 |
Bis-Tos-(2-hydroxyethyl disulfide) is a bifunctional disulfide ADC linker with tosylate leaving groups, enabling cleavable conjugation and controlled intracellular drug release in targeted antibody therapeutics. | Inquiry | |
BADC-01149 | mPEG3-amine | 74654-07-2 |
mPEG3-amine is a short-chain, amine-functionalized PEG linker offering compact size for ADC applications. Enhances solubility and stability of antibody-drug complexes while minimizing steric hindrance. | Inquiry | |
BADC-01151 | t-Boc-N-amido-PEG4-propionic acid | 756525-91-4 |
Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). | Inquiry |