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Cleavable Linker
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Cleavable Linker

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Catalog Product Name CAS Number
BADC-01092 PC SPDP-NHS carbonate ester 2279944-61-3
PC SPDP-NHS carbonate ester is a cleavable ADC linker with NHS ester for amine coupling and pyridyldithiol for thiol reactivity, supporting efficient antibody conjugation and controlled drug release. Inquiry
BADC-01094 mDPR(Boc)-Val-Cit-PAB 2281797-55-3
mDPR(Boc)-Val-Cit-PAB is a protected cleavable ADC linker with Val-Cit dipeptide and PAB spacer, designed for controlled enzymatic payload release and site-specific conjugation in antibody-drug conjugates. Inquiry
BADC-01095 MAC glucuronide linker-2 229977-57-5
MAC glucuronide linker-2 is an enzyme-cleavable ADC linker designed for targeted drug release within tumor microenvironments, enhancing therapeutic index and stability of antibody-drug conjugates. Inquiry
BADC-01096 BCN-PEG3-VC-PFP ester 2353409-45-5
BCN-PEG3-VC-PFP ester is a cleavable ADC linker with BCN for strain-promoted cycloaddition and Val-Cit dipeptide for enzymatic payload release, activated as PFP ester for amine coupling in ADC synthesis. Inquiry
BADC-01097 Mal-amido-PEG8-val-gly-PAB-OH 2353409-52-4
Mal-amido-PEG8-val-gly-PAB-OH is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01098 Biotin-PEG4-Dde-TAMRA-PEG3-Azide 2353409-56-8
Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01099 Mal-PEG8-Val-Cit-PAB-MMAE 2353409-69-3
Mal-PEG8-Val-Cit-PAB-MMAE is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01100 Gly-Gly-Gly-PEG4-DBCO 2353409-80-8
Gly-Gly-Gly-PEG4-DBCO is a flexible peptide-PEG hybrid ADC linker featuring DBCO for efficient SPAAC click chemistry, improving conjugation kinetics and antibody-drug conjugate stability. Inquiry
BADC-01101 Gly-Gly-Gly-PEG3-TCO 2353409-81-9
Gly-Gly-Gly-PEG3-TCO is a peptide-PEG hybrid ADC linker featuring trans-cyclooctene for rapid and selective inverse electron-demand Diels–Alder (IEDDA) click chemistry in targeted antibody-drug conjugate synthesis. Inquiry
BADC-01102 Gly-Gly-Gly-PEG4-methyltetrazine 2353409-82-0
Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01103 PC Biotin-PEG3-NHS ester 2353409-93-3
PC Biotin-PEG3-NHS ester is a multifunctional ADC linker combining biotin affinity, PEG spacer, and NHS ester reactivity to enable efficient antibody conjugation, purification, and enhanced targeting in antibody-drug conjugate workflows. Inquiry
BADC-01104 Fmoc-Gly-Gly-Phe-OtBu 236426-37-2
Fmoc-Gly-Gly-Phe-OtBu is a protected peptide ADC linker intermediate used for protease-sensitive drug release, enabling site-specific antibody conjugation and improved therapeutic index in ADC development. Inquiry
BADC-01105 Azide-PEG5-Tos 236754-49-7
Azide-PEG5-Tos is an ADC linker with PEG5 spacer and azide reactive group, designed for strain-promoted azide-alkyne cycloaddition. It enhances conjugation efficiency and improves stability in targeted antibody-drug conjugate synthesis. Inquiry
BADC-01108 MC-Gly-Gly-Phe-Gly 2413428-36-9
MC-Gly-Gly-Phe-Gly is a protease-cleavable ADC linker with peptide sequences designed for tumor-selective drug release, increasing the therapeutic window of antibody-drug conjugates. Inquiry
BADC-01110 Boc-Aminooxy-PEG2-bromide 252378-67-9
Boc-Aminooxy-PEG2-bromide is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-01111 Azido-PEG3-t-butyl ester 252881-73-5
N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. Inquiry
BADC-01112 Fmoc-N-amido-PEG1-acetic acid 260367-12-2
Fmoc-N-amido-PEG1-acetic acid is a PEGylated linker intermediate featuring an Fmoc-protected amide, enabling peptide elongation or payload attachment in ADC systems. Its hydrophilic PEG spacer improves solubility and flexibility, facilitating efficient antibody-drug conjugate construction. Inquiry
BADC-01114 N-Boc-N-bis(PEG2-OH) 275385-03-0
N-Boc-N-bis(PEG2-OH) is a Boc-protected bifunctional PEG linker with two hydroxyl groups, enabling flexible ADC linker synthesis and payload attachment. Its PEG chains enhance hydrophilicity and biocompatibility, improving antibody-drug conjugate solubility and stability. Inquiry
BADC-01115 mPEG2-amine 31576-51-9
mPEG2-amine is a short PEG linker with terminal amine functionality, used for efficient conjugation in ADC linker design. Its PEG2 spacer improves aqueous solubility and helps reduce immunogenicity in antibody-drug conjugates and other bioconjugate systems. Inquiry
BADC-01116 t-Boc-N-amido-PEG6-alcohol 331242-61-6
t-Boc-N-amido-PEG6-alcohol serves as a protected amino-PEG linker in antibody-drug conjugate synthesis. It provides flexible chain length and hydrophilicity for spacer arm design in multifunctional linker systems. Inquiry
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