webinar
Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
Read More
webinar
August 17–21, 2025, Washington, DC, USA - Visit us at Booth 2230.
Read More
Cleavable Linker
Filter Criteria
By Category
By SubCategory
By Functional Group
By Formula Weight

Cleavable Linker

Filtered by
Clear All
Catalog Product Name CAS Number
BADC-01068 Tetrazine-SS-Biotin 2123482-78-8
Tetrazine-SS-Biotin is a cleavable disulfide-containing ADC linker with tetrazine bioorthogonal reactivity and biotin affinity, enabling rapid conjugation, purification, and controlled drug release in antibody-drug conjugates. Inquiry
BADC-01069 S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate 2127875-65-2
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a cleavable sulfonothioate ADC linker supporting site-specific antibody conjugation and payload release in tumor environments. Inquiry
BADC-01070 Boc-aminooxy-ethyl-SS-propanol 2128735-21-5
Boc-aminooxy-ethyl-SS-propanol is a cleavable ADC linker featuring aminooxy functionality and disulfide bonds, enabling oxime ligation conjugation methods in antibody-drug conjugate synthesis. Inquiry
BADC-01071 Fmoc-NH-ethyl-SS-propionic NHS ester 2128735-23-7
Fmoc-NH-ethyl-SS-propionic NHS ester is a reactive ADC linker enabling efficient amine coupling with Fmoc protection and cleavable disulfide bonds. Supports precise antibody-drug conjugate synthesis for targeted therapy. Inquiry
BADC-01072 Mal-NH-ethyl-SS-propionic acid 2128735-24-8
Mal-NH-ethyl-SS-propionic acid is a maleimide-based cleavable ADC linker facilitating thiol conjugation and controlled drug release. Widely used in antibody-drug conjugate design for enhanced stability and efficacy. Inquiry
BADC-01073 DBCO-PEG5-NHS ester 2144395-59-3
DBCO-PEG5-NHS ester is a bifunctional ADC linker combining a DBCO group for copper-free click chemistry and an NHS ester for amine-reactive conjugation. Ideal for antibody-drug conjugates, it enables site-specific bioconjugation, improves hydrophilicity, and ensures stable payload attachment under physiological conditions. Inquiry
BADC-01074 Azido-C2-SS-PEG2-C2-acid 2144777-72-8
Azido-C2-SS-PEG2-C2-acid is a disulfide-containing ADC linker with azide and PEG spacers, enabling stable, cleavable antibody conjugation and efficient payload release via bioorthogonal click chemistry. Inquiry
BADC-01075 Amino-ethyl-SS-PEG3-NHBoc 2144777-87-5
Amino-ethyl-SS-PEG3-NHBoc is a PEGylated cleavable ADC linker featuring Boc-protected amine and disulfide bonds. Ideal for antibody conjugation with enhanced solubility and triggered drug release in therapeutic ADCs. Inquiry
BADC-01076 Azido-PEG5-CH2COOH 217180-81-9
Azido-PEG5-CH2COOH is a PEG derivative containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. Inquiry
BADC-01077 DBCO-PEG4-DBCO 2182601-68-7
DBCO-PEG4-DBCO is a dual-functional ADC linker with two DBCO moieties, designed for bioorthogonal SPAAC reactions. Its PEG4 spacer enhances solubility and flexibility, making it suitable for antibody or payload crosslinking in ADC synthesis and other targeted drug delivery platforms. Inquiry
BADC-01078 Propargyl-PEG8-NHS ester 2182601-74-5
Propargyl-PEG8-NHS ester serves as an advanced ADC linker providing PEG8 spacer length to enhance flexibility. Its alkyne and NHS ester groups enable efficient payload conjugation via click chemistry in targeted antibody-drug conjugate applications. Inquiry
BADC-01079 TCO-PEG12-NHS ester 2185016-39-9
TCO-PEG12-NHS ester is a long-chain linker for bioorthogonal ADC synthesis. It features a TCO moiety for click chemistry and an NHS ester for efficient amine coupling, providing optimal spacing and solubility. Inquiry
BADC-01080 Bis-PEG17-NHS ester 2221948-93-0
Bis-PEG17-NHS ester is a long-chain bifunctional PEG linker with dual NHS esters for efficient amine coupling in ADCs. It enhances hydrophilicity and steric spacing between antibody and payload, improving pharmacokinetics and reducing immunogenicity in targeted drug delivery. Inquiry
BADC-01081 Bis-PEG25-NHS ester 2221948-96-3
Bis-PEG25-NHS ester features a long PEG spacer with dual NHS esters, widely used in ADC linker design for hydrophilic and flexible bioconjugation. This linker improves solubility and reduces aggregation, enhancing the therapeutic index of antibody-drug conjugates. Inquiry
BADC-01082 Bis-PEG21-NHS ester 2221948-98-5
Bis-PEG21-NHS ester is a bifunctional PEG linker optimized for antibody-drug conjugates, providing extended hydrophilic spacing. Its dual NHS groups allow efficient amine coupling, facilitating stable and homogeneous conjugate formation in targeted therapies. Inquiry
BADC-01083 Bis-PEG13-NHS ester 2221949-00-2
Bis-PEG13-NHS ester is a non-cleavable 13-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Inquiry
BADC-01084 Bis-PEG10-NHS ester 2221949-02-4
Bis-PEG10-NHS ester is a non-cleavable 10-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Inquiry
BADC-01086 Azidoethyl-SS-propionic acid 2228857-32-5
Azidoethyl-SS-propionic acid is a cleavable disulfide-containing ADC linker with azide functionality, supporting bioorthogonal click chemistry and controlled intracellular payload release. Inquiry
BADC-01088 Azidoethyl-SS-propionic NHS ester 2243566-44-9
Azidoethyl-SS-propionic NHS ester is an amine-reactive, cleavable ADC linker with azide and disulfide groups, facilitating site-specific antibody conjugation and tumor-selective drug release. Inquiry
BADC-01089 DBCO-PEG3 acetic-EVCit-PAB 2253947-17-8
DBCO-PEG3 acetic-EVCit-PAB is a PEGylated ADC linker with click chemistry DBCO and enzymatically cleavable EVCit-PAB, designed to improve conjugate stability and controlled payload release in ADCs. Inquiry
Questions & Comments
Verification code
Inquiry Basket