Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00009 | DM1-SMCC | 1228105-51-8 |
| DM1 with a reactive linker SMCC, which can react with antibody to make antibody drug conjugate, as a potent EGFR inhibitor and it overcomes resistant to EGFR. | Inquiry | |
| BADC-00010 | DM1-SPP | 452072-20-7 |
| DM1 with a reactive linker SPP, which can react with antibody to make antibody drug conjugate, as a potent EGFR inhibitor and it overcomes resistant to EGFR. | Inquiry | |
| BADC-00011 | DM4-SPDP | 2245698-48-8 |
| DM4 with a reactive linker SPDP, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. | Inquiry | |
| BADC-00012 | DM4-SPDB | 1626359-62-3 |
| DM4 with a reactive linker SPDB, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. | Inquiry | |
| BADC-00021 | DM4-SMe | 796073-68-2 |
| DM4-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). . | Inquiry | |
| BADC-00022 | DM3-SMe | 796073-70-6 |
| DM3-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). . | Inquiry | |
| BADC-00086 | Mertansine | 139504-50-0 |
| Mertansine, the cytotoxic component in antibody-drug conjugates, is attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker or SMCC (4-(3-mercapto-2,5-dioxo-1 pyrrolidinylmethyl)-cylohexanecarboxylic acid) linkerto create an antibody-drug conjugate. It derives from a maytansine. | Inquiry | |
| BADC-00339 | DM3 | 796073-54-6 |
| DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00347 | DM4 | 796073-69-3 |
| DM4 is an anti-tubulin agent that inhibits cell division. DM4 can be used to prepare antibody-drug conjugates. DM4 binds to tubulin at the maytansine-binding site, disrupting microtubule assembly/disassembly dynamics and inhibiting mitosis. | Inquiry | |
| BADC-00357 | Ansamitocin P-3 | 66584-72-3 |
| It is produced by the strain of Nocardia sp. C-15003(N-1). It has the function of anti-tumor, anti-plant pathogenic fungi, skin fungi and protozoa, and has no antibacterial activity. | Inquiry | |
| BADC-00687 | N-Me-L-Ala-maytansinol | 77668-69-0 |
| N-Me-L-Ala-maytansinol is a hydrophobic, cell permeable payload used in the preparation of antibody-drug conjugate (ADC). | Inquiry | |
| BADC-00017 | DM4-SMCC | 1228105-52-9 |
| DM4 with a reactive linker SMCC, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. | Inquiry | |
| BADC-00087 | Maytansinoid DM4 | 799840-96-3 |
| DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00574 | Lys-SMCC-DM1 | 1281816-04-3 |
| Lys-SMCC-DM1 is the active metabolite of DM1. DM1 is a tubulin inhibitor. | Inquiry | |
| BADC-00600 | Sulfo-PDBA-DM4 | 1461704-01-7 |
| Sulfo-PDBA-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Sulfo-PDBA to make antibody drug conjugate (ADC). Sulfo-PDBA is a gluthatione cleavable linker. | Inquiry | |
| BADC-00601 | Mal-VC-PAB-DM1 | 1464051-44-2 |
| Mal-VC-PAB-DM1 is a drug-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB. | Inquiry | |
| BADC-00848 | MC-DM1 | 1375089-56-7 |
| MC-DM1 is a drug-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker MC to make antibody drug conjugate (ADC). | Inquiry | |
| BADC-00852 | Mc-Dexamethasone | 1618096-56-2 |
| Mc-Dexamethasone is a drug-linker conjugate for ADC. Mc-Dexamethasone is made toxin Dexamethasone (HY-14648) conjugated to the non-cleavable MC linker. Dexamethasone is a glucocorticoid receptor agonist. | Inquiry | |
| BADC-01351 | Maytansinoid B | 1628543-40-7 |
| Maytansinoid B is a kind of ADC Cytotoxin. Maytansinoids are potent microtubule-targeted compounds that inhibit proliferation of cells at mitosis. It is used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-01378 | S-methyl DM1 | 912569-84-7 |
| S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds tubulin with a Kd of 0.93 μM and inhibits microtubule polymerization. S-methyl DM1 can effectively inhibit microtubule dynamic instability and has anticancer effects. | Inquiry |
