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ADC Linker
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ADC Linker

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Catalog Product Name CAS Number
BADC-02015 (21S,24S)-tert-Butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-24-((4-(hydroxymethyl)phenyl)carbamoyl)-21-isopropyl-3,19,22-trioxo-7,10,13,16-tetraoxa-4,20,23-triazaheptacosan-27-oate
It is an ADC linker used in antibody-conjugated drugs. Inquiry
BADC-02016 t-Boc-aminooxy-PEG3-propargyl 1951439-46-5
t-Boc-aminooxy-PEG3-propargyl is a crosslinker containing a propargyl group and t-Boc-aminooxy group. t-Boc-aminooxy-PEG3-propargyl can be used as an ADC linker. Inquiry
BADC-02017 Azidoethyl-SS-ethylamine hydrochloride 2712401-25-5
Azidoethyl-SS-ethylamine hydrochloride is a cleavable ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs). Inquiry
BADC-02018 Poc-AEEA DCHA
Poc-AEEA DCHA is a derivative with a propargyloxycarbonyl (Poc) group and an AEEA (2-(2-aminoethoxy)ethoxy acetic acid) linker, existing as a dicyclohexylammonium (DCHA) salt. It is used in bioconjugation and peptide synthesis for introducing alkyne-functionalized residues that can participate in click chemistry reactions, enabling site-specific modifications and functionalization. Inquiry
BADC-02019 Poc-AEEA 2988660-57-5
Poc-AEEA is a derivative with a propargyloxycarbonyl (Poc) group and an AEEA (2-(2-aminoethoxy)ethoxy acetic acid) linker. It is used in bioconjugation and peptide synthesis for introducing alkyne-functionalized residues that can participate in click chemistry reactions, enabling site-specific modifications and functionalization. Inquiry
BADC-02021 N1-Azido-spermine 1190203-77-0
N1-Azido-spermine is a derivative of spermine with an azide (N3) group attached to the N1 position. It is used in chemical and biological research for its ability to participate in click chemistry reactions, enabling site-specific modifications and functionalization. Inquiry
BADC-02022 N3-DABu-Suc-OH 2226183-50-0
N3-DABu-Suc-OH can be used as an ADC (Antibody-Drug Conjugate) linker. It features an azide (N3) group attached to a butylenediamine (DABu) moiety and a succinoyl (Suc) group at the end. This compound is used in click chemistry and other conjugation reactions, particularly for labeling and functionalizing biomolecules through copper-catalyzed or copper-free click reactions. This structure allows for the attachment of a cytotoxic payload to an antibody through the succinoyl group, while the azide group can be used for further functionalization or conjugation reactions. Inquiry
BADC-02023 N3-DAPr-Suc-OH 929894-58-6
N3-DAPr-Suc-OH can be used as an ADC (Antibody-Drug Conjugate) linker. It features an azide (N3) group attached to a propylenediamine (DAPr) moiety and a succinoyl (Suc) group at the end. This structure allows for the attachment of a cytotoxic payload to an antibody through the succinoyl group, while the azide group can be used for further functionalization or conjugation reactions. Inquiry
BADC-02024 Boc-Cystamine-Suc-OH 946849-79-2
Boc-Cystamine-Suc-OH is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It features a Boc (tert-butyloxycarbonyl) protecting group and a succinyl (Suc) linker, making it suitable for attaching cytotoxic drugs to antibodies. This linker is designed to be stable in circulation but can be cleaved in the tumor microenvironment, allowing for controlled drug release and enhancing the effectiveness of ADCs. Inquiry
BADC-02025 Fmoc-Cystamine-Suc 946849-80-5
Fmoc-Cystamine-Suc-OH is a compound used in solid-phase peptide synthesis (SPPS) and bioconjugation applications. It features an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group and a succinyl (Suc) linker, making it suitable for constructing peptide sequences with specific functional groups. Inquiry
BADC-02026 Mal(Br2)-Aca-OSu 2389064-41-7
Mal(Br2)-Aca-OSu is a bioconjugation reagent used in antibody-drug conjugate (ADC) synthesis. It features a dibromo maleimide group and an aminocaproic acid (Aca) linker, terminated with an N-hydroxysuccinimide (OSu) ester. This compound is designed for conjugating antibodies to cytotoxic drugs, with the dibromo maleimide group facilitating selective attachment to thiol groups in the antibody. Inquiry
BADC-02027 Fmoc-Cystamine hydrochloride 2893917-85-4
Fmoc-Cystamine hydrochloride can be used as an ADC linker. It is a cleavable linker that can be reduced under reducing conditions to release the payload. This type of linker is useful for creating ADCs that can selectively release their cytotoxic payload in the reducing environment of cells, thereby minimizing off-target effects. Inquiry
BADC-02028 Fmoc-Cystamine 2576471-32-2
Fmoc-Cystamine can be used as an ADC linker. It is a cleavable linker that can be reduced under reducing conditions to release the payload. This type of linker is useful for creating ADCs that can selectively release their cytotoxic payload in the reducing environment of cells, thereby minimizing off-target effects. Inquiry
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